| Akcje zaległe | 15,801,901 shares |
| Akcje insidera | 8 617 263 shares |
| Własność insidera | 54,53 % |
| Insiderzy ogółem | 44 |
Wynik sentymentu insiderów
Ocena sentymentu insiderów pokazuje firmy, które są kupowane przez insiderów korporacyjnych.
Jest to wynik zaawansowanego, wieloczynnikowego modelu ilościowego, który identyfikuje spółki o najwyższym poziomie akumulacji informacji poufnych. Model rankingowy wykorzystuje kombinację liczby netto insiderów kupujących w ciągu ostatnich 90 dni, całkowitej liczby akcji kupionych jako procent akcji w obrocie oraz całkowitej liczby akcji posiadanych przez insiderów. Liczba ta waha się od 0 do 100, przy czym wyższe liczby wskazują na wyższy poziom akumulacji w porównaniu z innymi spółkami, a 50 to średnia.
Częstotliwość aktualizacji: codziennie
Ocena sentymentu kadry kierowniczej
Ocena sentymentu kadry kierowniczej pokazuje, że firmy są kupowane przez urzędników korporacyjnych.
Z definicji dyrektorzy korporacyjni to insiderzy korporacyjni, ale w przeciwieństwie do niektórych innych insiderów (10% akcjonariuszy i członków zarządu), dyrektorzy pracują dla firmy na co dzień i podczas handlu korzystają z własnych pieniędzy. (10% Akcjonariusze i członkowie zarządu często zarządzają funduszami zarządzających pieniędzmi innych osób). W związku z tym transakcje wykorzystujące informacje poufne dokonywane przez osoby z kadry kierowniczej mają znacznie większe znaczenie i powinny być odpowiednio traktowane.
Podobnie jak ocena sentymentu insiderów, ocena sentymentu kadry kierowniczej jest wynikiem zaawansowanego, wieloczynnikowego modelu ilościowego, który identyfikuje firmy o najwyższym poziomie akumulacji urzędników.
Częstotliwość aktualizacji: codziennie
Kluczowe wskaźniki insider
Ta karta pokazuje pozycję firmy według różnych wskaźników insider. Ranking według miary percentyla pokazuje, jak ta firma wypada na tle innych firm na rynkach amerykańskich. Wyższe rankingi wskazują na lepszą sytuację.
Na przykład ogólnie przyjmuje się, że kupowanie przez insiderów jest pozytywnym wskaźnikiem, zatem spółki z większą liczbą takich transakcji plasowałyby się wyżej niż spółki z mniejszą liczbą takich transakcji (lub nawet sprzedaży przez insiderów.
Liczba netto zakupów dokonanych przez insiderów (ranking)
10447 out of 10948
Liczba netto zakupów dokonanych przez insiderów to łączna liczba insiderów kupujących pomniejszona o całkowitą liczbę insiderów sprzedających w ciągu ostatnich 90 dni. Tutaj pokazana jest miara percentyla (zakres od 0 do 100%).
Procent akcji kupowanych przez insiderów (ranking)
10495 out of 10786
Procent akcji zakupionych przez insiderów to całkowita liczba akcji zakupionych przez insiderów pomniejszona o całkowitą liczbę akcji sprzedanych przez insiderów w ciągu ostatnich 90 dni, podzielona przez całkowitą liczbę akcji zakupionych przez insiderów i pomnożona przez 100.
Wykres handlu insider
Poniższy wykres przedstawia Neurogene Inc. transakcji zrealizowanych przez insiderów. Insiderzy to członkowie kadry kierowniczej, dyrektorzy lub znaczący inwestorzy w spółce. Ogólnie rzecz biorąc, dokonywanie transakcji w ich firmach przez osoby posiadające dostęp do informacji poufnych w oparciu o istotne, niepubliczne informacje jest generalnie nielegalne. Nie oznacza to, że dokonywanie jakichkolwiek transakcji we własnych firmach jest nielegalne. Muszą jednak zgłaszać wszystkie transakcje do SEC za pośrednictwem formularza 4.
Lista insiderów i wskaźniki rentowności
Ta tabela przedstawia listę znanych insiderów i jest generowana automatycznie na podstawie zgłoszeń ujawnianych SEC. Oprócz nazwisk, najnowszego tytułu oraz oznaczenia dyrektora, członka kierownictwa lub 10% właściciela, podajemy najnowsze ujawnione pakiety akcji. Dodatkowo, jeśli to możliwe, udostępniamy historyczne wyniki handlowe danego insidera. Historyczne wyniki handlowe to średnia ważona wyników rzeczywistych transakcji zakupu na otwartym rynku dokonanych przez insiderów. Więcej informacji na temat sposobu obliczania tej wartości obejrzyj webinar na YouTube.
See our leaderboard of most profitable insider traders.
| Insider | Średni zysk (%) | Posiadane Akcje |
Podział korygujący |
|---|---|---|---|
| Kamran Alam CFO, Vice President Finance - [O] | 0 | 0 | |
|
Baker Bros. Advisors Lp
Director, 10% Owner -
[D]
|
1 658 190 | 1 658 190 | |
|
Julian Baker
10% Owner -
|
3 501 691 | 1 658 190 | |
| Martin Babler | 25 000 | ||
|
Baker Bros. Advisors (GP) LLC
10% Owner -
|
25 000 | 1 658 190 | |
| Meta Cantey Boyd | 0 | ||
| Gary Bridger Director - [D] | 0 | 0 | |
| Stuart Cobb Chief Scientific Officer - [O] | 30 497 | 30 497 | |
| Donna Cochener | 400 000 | ||
| Christine Mikail Cvijic President and CFO, Director - [D] [O] | 93 640 | 93 640 | |
| Jonathan G Drachman President and CEO, Director - [D] [O] | 100 000 | 20 000 | |
|
Jeremy Green
10% Owner -
|
4 041 211 | 808 242 | |
| Robert Ho Chief Financial Officer - [O] | 21 503 | 4 301 | |
|
& Johnson Johnson
10% Owner -
|
100 000 | 100 000 |
| Insider | Średni zysk (%) | Posiadane Akcje |
Podział korygujący |
|---|---|---|---|
| Abigail Jenkins Chief Commercial Officer - [O] | 0 | 0 | |
|
Johnson & Johnson Innovation - JJDC, Inc.
10% Owner -
|
100 000 | 100 000 | |
| Elaine V Jones Director - [D] | 0 | 0 | |
| Julie Jordan Chief Medical Officer - [O] | 12 472 | 12 472 | |
| Daniel J Levitt Director - [D] | 0 | 0 | |
| Erin Lavelle | 25 000 | ||
| Lavelle Erin M. | 0 | ||
| Richard S Levy | 0 | ||
| Lloyd MacKenzie Chief Operating Officer - [O] | 0 | 0 | |
| David Main President and CEO, Director - [D] [O] | 71 530 | 71 530 | |
| Shelley McCloskey VP, HR and Administration - [O] | 0 | 0 | |
| Rachel McMinn Chief Executive Officer, Director - [D] [O] | 1 344 307 | 1 344 307 | |
| David Chilton Mitchell VP Global Regulatory & Quality - [O] | 3 575 | 3 575 | |
| Kelvin Neu Director - [D] | 72 | 72 | |
| Nolan Sean P. | 25 000 |
| Insider | Średni zysk (%) | Posiadane Akcje |
Podział korygujący |
|---|---|---|---|
| Noonberg Sarah B. | 25 000 | ||
| Rohan Palekar | 25 000 | ||
|
Pfizer Inc
10% Owner -
|
975 403 | 975 403 | |
| Priti Patel - | 37 313 | 7 463 | |
| Robert Pelzer | 15 000 | ||
|
Redmile Group, LLC
10% Owner -
|
4 041 211 | 808 242 | |
| Stephen B Shrewsbury CMO; Senior VP Clinical Dev. - [O] | 400 | 400 | |
| Todd E Simpson Director - [D] | 0 | 0 | |
|
Samsara BioCapital GP, LLC
10% Owner -
|
1 668 357 | 1 668 357 | |
| Sean Michael Smith Interim CFO, Prin Acct Off - [O] | 21 637 | 4 327 | |
| Barbara Troupin Chief Medical Officer - [O] | 0 | 0 | |
| Holly Vance | 100 000 | ||
|
Ventures West 8 Limited Partnership
10% Owner -
|
1 543 989 | 1 543 989 | |
| Carl Walkey Senior Vice President - [O] | 1 352 489 | 270 498 | |
| Lewis T Williams | 25 000 |
Report errors via our new Insider Auditing Tool
Śledź historię zakupów insiderów — analiza zysków krótkoterminowych
W tej sekcji analizujemy rentowność każdego nieplanowanego zakupu od poufnych informacji na otwartym rynku dokonanego w NGNE / Neurogene Inc.. Analiza ta pomaga zrozumieć, czy insider konsekwentnie generuje nietypowe zyski i czy warto ją śledzić. Analiza ta obejmuje okres jednego roku po każdej transakcji wyniki są teoretyczne .
Poniższa tabela przedstawia najnowsze zakupy na otwartym rynku, które nie były częścią planu handlu automatycznego.
Cena skorygowana to cena skorygowana o podział. Akcje skorygowane to akcje skorygowane o podział.
Śledź historię sprzedaży insider — analiza strat krótkoterminowych
W tej sekcji analizujemy możliwość uniknięcia krótkoterminowych strat w wyniku każdej nieplanowanej sprzedaży insidera na otwartym rynku dokonanej w NGNE / Neurogene Inc.. Konsekwentny wzorzec unikania strat może sugerować, że przyszłe transakcje sprzedaży mogą przewidywać spadki cen. Analiza ta obejmuje okres jednego roku po każdej transakcji wyniki są teoretyczne .
Poniższa tabela przedstawia najnowsze sprzedaże na otwartym rynku, które nie były częścią planu handlu automatycznego.
Cena skorygowana to cena skorygowana o podział. Akcje skorygowane to akcje skorygowane o podział.
Historia transakcji
Kliknij ikonę linku, aby zobaczyć pełną historię transakcji. Transakcje zgłoszone w ramach automatycznego planu handlowego 10b5-1 będą oznaczone znakiem X w kolumnie oznaczonej 10b-5.
| Plik Data |
Data transakcji |
Formularz | Wtajemniczony | Serce | Nazwa papieru wartościowego | Kod | Bezpośredni | Cena wykonania |
Cena jednostki |
Zmieniono jednostki |
Zmieniona wartość (1 tys.) |
Pozostałe opcje |
Pozostałe akcje |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-05-08 | 2026-05-06 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 32,4358 | -4 800 | -156 | 93 640 | ||||
| 2026-05-08 | 2026-05-06 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 30,0732 | -4 800 | -144 | 98 440 | ||||
| 2026-03-30 | 2026-03-26 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 21,6247 | -2 558 | -55 | 103 240 | ||||
| 2026-03-30 | 2026-03-26 | 4 | Jordan Julie | NGNE | Common Stock | D | 21,8932 | -828 | -18 | 12 472 | ||||
| 2026-03-30 | 2026-03-26 | 4 | McMinn Rachel | NGNE | Common Stock | D | 22,0749 | -3 352 | -74 | 1 344 307 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 22,0195 | -263 | -6 | 105 798 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 21,2451 | -1 395 | -30 | 106 061 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20,4224 | -2 387 | -49 | 107 456 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 22,0800 | -148 | -3 | 30 497 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 21,3400 | -2 658 | -57 | 30 645 | ||||
| 2026-03-17 | 2026-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 20,4100 | -3 991 | -81 | 33 303 | ||||
| 2026-03-03 | 2026-02-27 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 25,1096 | -4 800 | -121 | 109 843 | ||||
| 2026-02-24 | 2026-02-20 | 4 | Cobb Stuart | NGNE | Common Stock | D | 16 500 | 37 294 | ||||||
| 2026-02-24 | 2026-02-20 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 22 000 | 114 643 | ||||||
| 2026-02-24 | 2026-02-20 | 4 | Jordan Julie | NGNE | Common Stock | D | 4 900 | 13 300 | ||||||
| 2026-02-24 | 2026-02-20 | 4 | McMinn Rachel | NGNE | Common Stock | D | 25 900 | 1 347 659 | ||||||
| 2025-05-15 | 2025-05-14 | 4 | Cobb Stuart | NGNE | Common Stock | D | 15,1542 | -6 797 | -103 | 20 794 | ||||
| 2025-03-28 | 2025-03-26 | 4 | Cobb Stuart | NGNE | Common Stock | D | 7 200 | 27 591 | ||||||
| 2025-03-28 | 2025-03-26 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20 300 | 92 643 | ||||||
| 2025-03-28 | 2025-03-26 | 4 | Jordan Julie | NGNE | Common Stock | D | 8 400 | 8 400 | ||||||
| 2025-03-28 | 2025-03-26 | 4 | McMinn Rachel | NGNE | Common Stock | D | 23 900 | 1 274 259 | ||||||
| 2025-03-17 | 2025-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 16,9400 | -4 501 | -76 | 72 343 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 27,5000 | 2 000 | 55 | 1 717 127 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 26,7300 | 15 219 | 407 | 1 715 127 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 26,0100 | 10 803 | 281 | 1 699 908 | ||||
| 2024-11-27 | 2024-11-26 | 4 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 24,9100 | 20 748 | 517 | 1 689 105 | ||||
| 2024-11-27 | 3 | Samsara BioCapital GP, LLC By Samsara BioCapital, L.P. | NGNE | Common Stock | I | 1 668 357 | ||||||||
| 2024-11-25 | 2024-11-22 | 4 | McMinn Rachel | NGNE | Common Stock | D | 20,4000 | 47 500 | 969 | 1 297 859 | ||||
| 2024-11-25 | 2024-11-22 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20,4750 | 24 000 | 491 | 76 844 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Cvijic Christine Mikail | NGNE | Common Stock | D | 31 903 | 52 844 | ||||||
| 2024-03-14 | 2024-03-13 | 4 | Cobb Stuart | NGNE | Common Stock | D | 20 391 | 20 391 | ||||||
| 2023-12-26 | 3 | Cvijic Christine Mikail | NGNE | Common Stock | D | 20 941 | ||||||||
| 2023-12-26 | 3 | McMinn Rachel | NGNE | Common Stock | D | 1 250 359 | ||||||||
| 2023-10-10 | 2023-10-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 535 601 | 1 658 190 | ||||||
| 2023-10-10 | 2023-10-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 57 049 | 155 874 | ||||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6928 | 61 134 | 42 | 5 612 949 | ||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6928 | 5 041 | 3 | 494 133 | ||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6924 | 93 091 | 64 | 5 551 815 | ||||
| 2023-08-17 | 2023-08-17 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6924 | 7 676 | 5 | 489 092 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6828 | 4 434 | 3 | 5 458 724 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6828 | 366 | 0 | 481 416 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6805 | 207 676 | 141 | 5 454 290 | ||||
| 2023-08-17 | 2023-08-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6805 | 17 124 | 12 | 481 050 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6650 | 4 342 | 3 | 5 246 614 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6650 | 358 | 0 | 463 926 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6308 | 1 740 581 | 1 098 | 5 242 272 | ||||
| 2023-08-17 | 2023-08-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 0,6308 | 143 519 | 91 | 463 568 | ||||
| 2023-08-14 | 2023-08-11 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 0,6184 | -1 323 | -1 | 21 637 | ||||
| 2023-08-14 | 2023-08-10 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 5 000 | 22 960 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Patel Priti | NLTX | Common Stock | D | 0,6919 | -3 769 | -3 | 37 313 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Patel Priti | NLTX | Common Stock | D | 10 000 | 41 082 | ||||||
| 2023-02-03 | 2023-02-02 | 4 | Patel Priti | NLTX | Common Stock | D | 0,5972 | -14 380 | -9 | 31 082 | ||||
| 2023-02-03 | 2023-02-01 | 4 | Patel Priti | NLTX | Common Stock | D | 35 000 | 45 462 | ||||||
| 2023-02-03 | 2023-02-02 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 0,5972 | -3 316 | -2 | 15 960 | ||||
| 2023-02-03 | 2023-02-01 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 12 500 | 19 276 | ||||||
| 2022-08-12 | 2022-08-10 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 0,9914 | -1 655 | -2 | 6 776 | ||||
| 2022-08-12 | 2022-08-10 | 4 | Smith Sean Michael | NLTX | Common Stock | D | 5 000 | 8 431 | ||||||
| 2022-05-16 | 2022-05-12 | 4 | SIMPSON TODD E | NLTX | Stock Option (Right to Buy) | D | 1,07 | 25 000 | 25 000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | PALEKAR ROHAN | NLTX | Stock Option (Right to Buy) | D | 1,07 | 25 000 | 25 000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | Lavelle Erin | NLTX | Stock Option (Right to Buy) | D | 1,07 | 25 000 | 25 000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | Noonberg Sarah B. | NLTX | Stock Option (Right to Buy) | D | 1,07 | 25 000 | 25 000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | Babler Martin | NLTX | Stock Option (Right to Buy) | D | 1,07 | 25 000 | 25 000 | |||||
| 2022-05-16 | 2022-05-12 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 1,07 | 25 000 | 25 000 | |||||
| 2022-05-03 | 2022-05-02 | 4 | Patel Priti | NLTX | Common Stock | D | 1,2186 | -5 538 | -7 | 6 462 | ||||
| 2022-05-03 | 2022-04-30 | 4 | Patel Priti | NLTX | Restricted Stock Units | D | 0,00 | 10 000 | 10 000 | |||||
| 2022-05-03 | 2022-04-30 | 4 | Patel Priti | NLTX | Common Stock | D | 10 000 | 12 000 | ||||||
| 2022-03-15 | 2022-03-14 | 4 | Cochener Donna | NLTX | Stock Option (Right to Buy) | D | 1,81 | 400 000 | 400 000 | |||||
| 2022-03-04 | 2022-03-02 | 4 | PALEKAR ROHAN | NLTX | Stock Option (Right to Buy) | D | 2,72 | 50 000 | 50 000 | |||||
| 2022-03-03 | 3 | Smith Sean Michael | NLTX | Common Stock | D | 3 431 | ||||||||
| 2022-03-03 | 2022-03-02 | 4 | Smith Sean Michael | NLTX | Stock Option (Right to Buy) | D | 2,72 | 80 000 | 80 000 | |||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 75 000 | 100 000 | ||||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 75 000 | 100 000 | ||||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | -75 000 | 2 198 686 | ||||||
| 2022-02-14 | 2021-10-26 | 5 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | -75 000 | 2 198 686 | ||||||
| 2022-02-02 | 2022-02-01 | 4 | Walkey Carl | NLTX | Restricted Stock Units | D | 0,00 | 55 000 | 55 000 | |||||
| 2022-02-02 | 2022-02-01 | 4 | Patel Priti | NLTX | Restricted Stock Units | D | 0,00 | 70 000 | 70 000 | |||||
| 2022-02-02 | 2022-02-01 | 4 | Ho Robert | NLTX | Restricted Stock Units | D | 0,00 | 70 000 | 70 000 | |||||
| 2021-08-26 | 2021-08-25 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 6,4490 | 25 000 | 161 | 25 000 | ||||
| 2021-08-26 | 2021-08-25 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | I | 6,4490 | 25 000 | 161 | 25 000 | ||||
| 2021-08-26 | 2021-08-24 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 6,1110 | 100 000 | 611 | 2 348 686 | ||||
| 2021-08-05 | 2021-08-03 | 4 | Walkey Carl | NLTX | Stock Option (Right to Buy) | D | 6,80 | 100 000 | 100 000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | Vance Holly | NLTX | Stock Option (Right to Buy) | D | 6,80 | 100 000 | 100 000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | Patel Priti | NLTX | Stock Option (Right to Buy) | D | 6,80 | 50 000 | 50 000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | Ho Robert | NLTX | Stock Option (Right to Buy) | D | 6,80 | 190 000 | 190 000 | |||||
| 2021-08-05 | 2021-08-03 | 4 | DRACHMAN JONATHAN G | NLTX | Stock Option (Right to Buy) | D | 6,80 | 400 000 | 400 000 | |||||
| 2021-06-17 | 2021-06-16 | 4 | Walkey Carl | NLTX | Common Stock | D | 10,1900 | -600 | -6 | 1 352 489 | ||||
| 2021-06-11 | 2021-06-09 | 4 | Walkey Carl | NLTX | Common Stock | D | 10,8246 | -650 | -7 | 1 353 089 | ||||
| 2021-06-09 | 2021-06-08 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,0000 | -600 | -7 | 1 353 739 | ||||
| 2021-06-07 | 2021-06-04 | 4 | Walkey Carl | NLTX | Common Stock | D | 10,0000 | -600 | -6 | 1 354 339 | ||||
| 2021-06-07 | 2021-06-04 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 9,6082 | 10 000 | 96 | 2 248 686 | ||||
| 2021-06-07 | 2021-06-03 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 9,4818 | 40 000 | 379 | 2 238 686 | ||||
| 2021-05-26 | 2021-05-26 | 4 | Walkey Carl | NLTX | Common Stock | D | 10,0000 | -600 | -6 | 1 354 939 | ||||
| 2021-05-21 | 2021-05-19 | 4 | Walkey Carl | NLTX | Common Stock | D | 10,6300 | -600 | -6 | 1 355 539 | ||||
| 2021-05-13 | 2021-05-11 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 11,40 | 25 000 | 25 000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Babler Martin | NLTX | Stock Option (Right to Buy) | D | 11,40 | 25 000 | 25 000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Lavelle Erin M. | NLTX | Stock Option (Right to Buy) | D | 11,40 | 25 000 | 25 000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Noonberg Sarah B. | NLTX | Stock Option (Right to Buy) | D | 11,40 | 25 000 | 25 000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | Williams Lewis T | NLTX | Stock Option (Right to Buy) | D | 11,40 | 25 000 | 25 000 | |||||
| 2021-05-13 | 2021-05-11 | 4 | SIMPSON TODD E | NLTX | Stock Option (Right to Buy) | D | 11,40 | 25 000 | 25 000 | |||||
| 2021-05-12 | 2021-05-12 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,0900 | -1 200 | -13 | 1 354 762 | ||||
| 2021-05-06 | 2021-05-05 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,3000 | -1 200 | -14 | 1 355 962 | ||||
| 2021-05-04 | 2021-04-30 | 4 | Patel Priti | NLTX | Stock Option (Right to Buy) | D | 12,49 | 475 000 | 475 000 | |||||
| 2021-05-04 | 2021-04-30 | 4 | Patel Priti | NLTX | Restricted Stock Units | D | 0,00 | 20 000 | 20 000 | |||||
| 2021-04-30 | 2021-04-28 | 4 | Walkey Carl | NLTX | Common Stock | D | 12,5800 | -2 400 | -30 | 1 357 162 | ||||
| 2021-04-27 | 2021-04-26 | 4 | Walkey Carl | NLTX | Common Stock | D | 13,0000 | -600 | -8 | 1 359 562 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,9800 | -1 800 | -22 | 1 360 162 | ||||
| 2021-04-16 | 2021-04-14 | 4 | Walkey Carl | NLTX | Common Stock | D | 12,2200 | -1 800 | -22 | 1 361 962 | ||||
| 2021-04-08 | 2021-04-07 | 4 | Walkey Carl | NLTX | Common Stock | D | 12,0200 | -1 800 | -22 | 1 363 762 | ||||
| 2021-04-06 | 2021-04-05 | 4 | Walkey Carl | NLTX | Common Stock | D | 13,0000 | -600 | -8 | 1 365 562 | ||||
| 2021-04-02 | 2021-03-31 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,9600 | -1 800 | -22 | 1 366 162 | ||||
| 2021-03-24 | 2021-03-24 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,9533 | -1 800 | -22 | 1 367 962 | ||||
| 2021-03-24 | 2021-03-22 | 4 | Walkey Carl | NLTX | Common Stock | D | 12,0000 | -600 | -7 | 1 369 762 | ||||
| 2021-03-18 | 2021-03-17 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,3600 | -1 200 | -14 | 1 370 362 | ||||
| 2021-03-18 | 2021-03-17 | 4 | Ho Robert | NLTX | Common Stock | D | 11,0137 | -6 497 | -72 | 21 503 | ||||
| 2021-03-18 | 2021-03-16 | 4 | Ho Robert | NLTX | Restricted Stock Units | D | 0,00 | 25 000 | 50 000 | |||||
| 2021-03-18 | 2021-03-16 | 4 | Ho Robert | NLTX | Common Stock | D | 25 000 | 28 000 | ||||||
| 2021-03-11 | 2021-03-10 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,9667 | -1 800 | -22 | 1 371 562 | ||||
| 2021-03-04 | 2021-03-03 | 4 | Walkey Carl | NLTX | Common Stock | D | 11,8667 | -1 800 | -21 | 1 373 362 | ||||
| 2021-02-25 | 2021-02-25 | 4 | Walkey Carl | NLTX | Common Stock | D | 13,0000 | -600 | -8 | 1 375 162 | ||||
| 2021-02-25 | 2021-02-24 | 4 | Walkey Carl | NLTX | Common Stock | D | 12,1400 | -1 800 | -22 | 1 375 762 | ||||
| 2021-02-18 | 2021-02-17 | 4 | Walkey Carl | NLTX | Common Stock | D | 12,7000 | -2 400 | -30 | 1 377 562 | ||||
| 2021-02-12 | 2021-02-10 | 4 | Walkey Carl | NLTX | Common Stock | D | 14,2000 | -3 000 | -43 | 1 379 962 | ||||
| 2021-02-09 | 2021-02-05 | 4 | Walkey Carl | NLTX | Common Stock | D | 14,0000 | -600 | -8 | 1 382 962 | ||||
| 2021-02-05 | 2021-02-03 | 4 | Walkey Carl | NLTX | Common Stock | D | 13,2300 | -2 400 | -32 | 1 383 562 | ||||
| 2021-02-02 | 2021-01-30 | 4 | Walkey Carl | NLTX | Stock Option (Right to Buy) | D | 12,60 | 45 000 | 45 000 | |||||
| 2021-02-02 | 3 | Walkey Carl | NLTX | Common Stock | D | 1 385 962 | ||||||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-Funded Warrants | I | 518 555 | 10 283 888 | ||||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-Funded Warrants | I | 38 974 | 1 199 122 | ||||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 15,2500 | 394 360 | 6 014 | 3 501 691 | ||||
| 2020-12-23 | 2020-07-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 15,2500 | 29 640 | 452 | 320 049 | ||||
| 2020-10-20 | 2020-10-19 | 4 | Vance Holly | NLTX | Stock Option (Right to Buy) | D | 12,30 | 220 000 | 220 000 | |||||
| 2020-09-10 | 2020-09-08 | 4 | Babler Martin | NLTX | Stock Option (Right to Buy) | D | 12,25 | 50 000 | 50 000 | |||||
| 2020-08-12 | 2020-08-10 | 4 | DRACHMAN JONATHAN G | NLTX | Stock Option (Right to Buy) | D | 12,00 | 420 000 | 420 000 | |||||
| 2020-08-12 | 2020-08-10 | 4 | Ho Robert | NLTX | Stock Option (Right to Buy) | D | 12,00 | 90 000 | 90 000 | |||||
| 2020-06-02 | 2020-06-01 | 4 | Lavelle Erin M. | NLTX | Stock Option (Right to Buy) | D | 13,58 | 50 000 | 50 000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 12,84 | 25 000 | 25 000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | Nolan Sean P. | NLTX | Stock Option (Right to Buy) | D | 12,84 | 25 000 | 25 000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | Noonberg Sarah B. | NLTX | Stock Option (Right to Buy) | D | 12,84 | 25 000 | 25 000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | SIMPSON TODD E | NLTX | Stock Option (Right to Buy) | D | 12,84 | 25 000 | 25 000 | |||||
| 2020-05-07 | 2020-05-05 | 4 | Williams Lewis T | NLTX | Stock Option (Right to Buy) | D | 12,84 | 25 000 | 25 000 | |||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11,8200 | -100 | -1 | 4 041 211 | ||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11,3039 | -9 734 | -110 | 4 041 311 | ||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11,8506 | 1 000 | 12 | 4 051 045 | ||||
| 2020-04-06 | 2020-04-02 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11,3605 | 38 300 | 435 | 4 050 045 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11,8650 | -200 | -2 | 4 011 745 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11,0616 | -9 634 | -107 | 4 011 945 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 11,6517 | 9 000 | 105 | 4 021 579 | ||||
| 2020-04-06 | 2020-04-01 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10,9482 | 33 500 | 367 | 4 012 579 | ||||
| 2020-04-06 | 2020-03-31 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10,7079 | 7 500 | 80 | 3 979 079 | ||||
| 2020-04-06 | 2020-03-31 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10,1813 | 22 500 | 229 | 3 971 579 | ||||
| 2020-04-06 | 2020-03-30 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 10,2744 | 2 700 | 28 | 3 949 079 | ||||
| 2020-04-06 | 2020-03-30 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 9,9050 | 29 800 | 295 | 3 946 379 | ||||
| 2020-04-06 | 2020-03-27 | 4 | Redmile Group, LLC | NLTX | Common Stock | I | 9,2079 | 50 000 | 460 | 3 916 579 | ||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7 733 158 | ||||||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7 733 158 | ||||||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7 733 158 | ||||||||
| 2020-04-06 | 3 | Green Jeremy | NLTX | Common Stock | I | 7 733 158 | ||||||||
| 2020-03-16 | 3 | Ho Robert | NLTX | Common Stock | D | 6 000 | ||||||||
| 2020-03-16 | 3 | Ho Robert | NLTX | Common Stock | D | 6 000 | ||||||||
| 2020-03-16 | 3 | Ho Robert | NLTX | Common Stock | D | 6 000 | ||||||||
| 2020-03-16 | 2020-03-16 | 4 | Ho Robert | NLTX | Stock Option (Right to Buy) | D | 6,44 | 200 000 | 200 000 | |||||
| 2020-03-16 | 2020-03-16 | 4 | Ho Robert | NLTX | Restricted Stock Units | D | 0,00 | 75 000 | 75 000 | |||||
| 2019-12-20 | 2019-12-20 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 8,4000 | 119 047 | 1 000 | 2 198 686 | ||||
| 2019-12-20 | 2019-11-12 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 1 261 600 | 2 079 639 | ||||||
| 2019-12-20 | 2019-11-12 | 4 | DRACHMAN JONATHAN G | NLTX | Series A Preferred Stock | D | -12 616 | 0 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-funded Warrants | I | 9 765 333 | 9 765 333 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Pre-funded Warrants | I | 1 160 148 | 1 161 048 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | -9 765 333 | 3 107 331 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | -1 160 148 | 290 409 | ||||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 8,4000 | 2 767 505 | 23 247 | 12 872 664 | ||||
| 2019-12-20 | 2019-12-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Common Stock | I | 8,4000 | 250 037 | 2 100 | 1 450 557 | ||||
| 2019-10-15 | 2019-10-10 | 4 | BAKER BROS. ADVISORS LP See Footnotes | NLTX | Non-Qualified Stock Option (right to buy) | I | 2,82 | 22 000 | 22 000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Williams Lewis T | NLTX | Stock Option (right to buy) | D | 2,82 | 22 000 | 22 000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Nolan Sean P. | NLTX | Stock Option (right to buy) | D | 2,82 | 22 000 | 22 000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | Noonberg Sarah B. | NLTX | Stock Option (right to buy) | D | 2,82 | 22 000 | 22 000 | |||||
| 2019-10-15 | 2019-10-10 | 4 | SIMPSON TODD E | NLTX | Stock Option (right to buy) | D | 2,82 | 22 000 | 22 000 | |||||
| 2019-09-13 | 2019-08-08 | 4/A | DRACHMAN JONATHAN G | NLTX | Series A Preferred Stock | D | 12 616 | 12 616 | ||||||
| 2019-09-13 | 2019-08-08 | 4/A | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 568 039 | 568 039 | ||||||
| 2019-09-11 | 2019-09-11 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 3,2975 | 136 436 | 450 | 584 428 | ||||
| 2019-09-11 | 2019-09-10 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 3,0834 | 36 742 | 113 | 447 992 | ||||
| 2019-09-11 | 2019-09-09 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 2,8450 | 76 822 | 219 | 411 250 | ||||
| 2019-09-04 | 2019-08-31 | 4 | DRACHMAN JONATHAN G | NLTX | Stock Option (Right to Buy) | D | 2,80 | 1 650 000 | 1 650 000 | |||||
| 2019-08-12 | 2019-08-08 | 4 | DRACHMAN JONATHAN G | NLTX | Series A Preferred Stock | D | 7 428 | 7 428 | ||||||
| 2019-08-12 | 2019-08-08 | 4 | DRACHMAN JONATHAN G | NLTX | Common Stock | D | 334 428 | 334 428 | ||||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3,1529 | 50 436 | 159 | 10 105 159 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3,1529 | 4 564 | 14 | 1 200 520 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3,0244 | 209 382 | 633 | 10 054 723 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 3,0244 | 18 943 | 57 | 1 195 956 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2,9576 | 5 869 | 17 | 9 845 341 | ||||
| 2019-08-08 | 2019-08-07 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2,9576 | 531 | 2 | 1 177 013 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2,8469 | 65 568 | 187 | 9 839 472 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2,8469 | 5 932 | 17 | 1 176 482 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2,8328 | 9 445 | 27 | 9 773 904 | ||||
| 2019-08-08 | 2019-08-06 | 4 | BAKER BROS. ADVISORS LP See footnotes | AQXP | Common Stock | I | 2,8328 | 855 | 2 | 1 170 550 | ||||
| 2018-08-09 | 2018-08-07 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 3,07 | 195 000 | 195 000 | |||||
| 2018-08-09 | 2018-08-07 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 3,07 | 145 000 | 145 000 | |||||
| 2018-08-09 | 2018-08-07 | 4 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 3,07 | 75 000 | 75 000 | |||||
| 2018-08-09 | 2018-08-07 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 3,07 | 415 000 | 415 000 | |||||
| 2018-05-16 | 2018-05-14 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 10,56 | -3 906 | 0 | |||||
| 2018-05-16 | 2018-05-14 | 4 | LEVITT DANIEL J | AQXP | Common Stock | D | 12,6700 | -3 906 | -49 | 0 | ||||
| 2018-05-16 | 2018-05-14 | 4 | LEVITT DANIEL J | AQXP | Common Stock | D | 10,5600 | 3 906 | 41 | 3 906 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 13,10 | 15 000 | 15 000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 13,10 | 15 000 | 15 000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 13,10 | 15 000 | 15 000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 13,10 | 15 000 | 15 000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 13,10 | 15 000 | 15 000 | |||||
| 2018-05-09 | 2018-05-07 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Non-Qualified Stock Option (right to buy) | I | 13,10 | 30 000 | 30 000 | |||||
| 2018-03-19 | 2018-03-15 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 10,56 | -1 302 | 0 | |||||
| 2018-03-19 | 2018-03-15 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 14,6304 | -1 302 | -19 | 0 | ||||
| 2018-03-19 | 2018-03-15 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 10,5600 | 1 302 | 14 | 1 302 | ||||
| 2018-03-13 | 2018-03-09 | 4 | Troupin Barbara | AQXP | Stock Option (Right to Buy) | D | 16,55 | 75 000 | 75 000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 16,55 | 75 000 | 75 000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Jenkins Abigail | AQXP | Stock Option (Right to Buy) | D | 16,55 | 75 000 | 75 000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 16,55 | 75 000 | 75 000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 16,55 | 225 000 | 225 000 | |||||
| 2018-03-13 | 2018-03-09 | 4 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 16,55 | 45 000 | 45 000 | |||||
| 2017-06-05 | 2017-06-05 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 9,60 | -3 625 | 0 | |||||
| 2017-06-05 | 2017-06-05 | 4 | Main David | AQXP | Common Stock | D | 13,1575 | -3 625 | -48 | 71 530 | ||||
| 2017-06-05 | 2017-06-05 | 4 | Main David | AQXP | Common Stock | D | 9,6000 | 3 625 | 35 | 75 155 | ||||
| 2017-06-05 | 2017-06-02 | 4 | Main David | AQXP | Stock Option (Right to Buy( | D | 9,60 | -6 000 | 3 625 | |||||
| 2017-06-05 | 2017-06-02 | 4 | Main David | AQXP | Common Stock | D | 13,5933 | -6 000 | -82 | 71 530 | ||||
| 2017-06-05 | 2017-06-02 | 4 | Main David | AQXP | Common Stock | D | 9,6000 | 6 000 | 58 | 77 530 | ||||
| 2017-06-05 | 2017-06-01 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 9,60 | -6 000 | 9 625 | |||||
| 2017-06-05 | 2017-06-01 | 4 | Main David | AQXP | Common Stock | D | 12,9980 | -6 000 | -78 | 71 530 | ||||
| 2017-06-05 | 2017-06-01 | 4 | Main David | AQXP | Common Stock | D | 9,6000 | 6 000 | 58 | 77 530 | ||||
| 2017-05-10 | 2017-05-08 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 13,74 | 9 000 | 9 000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 13,74 | 9 000 | 9 000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 13,74 | 9 000 | 9 000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 13,74 | 9 000 | 9 000 | |||||
| 2017-05-10 | 2017-05-08 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 13,74 | 9 000 | 9 000 | |||||
| 2017-05-09 | 2017-05-08 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Non-Qualified Stock Option (right to buy) | I | 13,74 | 36 000 | 36 000 | |||||
| 2017-03-27 | 3 | Neu Kelvin | AQXP | Common Stock | D | 72 | ||||||||
| 2017-03-27 | 3 | Neu Kelvin | AQXP | Common Stock | D | 72 | ||||||||
| 2017-03-10 | 2017-03-08 | 4 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 17,35 | 30 000 | 30 000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Mitchell David Chilton | AQXP | Stock Option (Right to Buy) | D | 17,35 | 25 000 | 25 000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Troupin Barbara | AQXP | Stock Option (Right to Buy) | D | 17,35 | 40 000 | 40 000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 17,35 | 50 000 | 50 000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 17,35 | 185 000 | 185 000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 17,35 | 80 000 | 80 000 | |||||
| 2017-03-10 | 2017-03-08 | 4 | Jenkins Abigail | AQXP | Stock Option (Right to Buy) | D | 17,35 | 80 000 | 80 000 | |||||
| 2017-02-14 | 2016-01-10 | 5 | McCloskey Shelley | AQXP | Stock Option (Right to Buy) | D | 10,09 | 35 000 | 35 000 | |||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17,7600 | 32 051 | 569 | 9 764 459 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17,7600 | 3 389 | 60 | 1 169 695 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17,5996 | 235 169 | 4 139 | 9 732 408 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 17,5996 | 24 871 | 438 | 1 166 306 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,3053 | 35 360 | 577 | 9 497 239 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,3053 | 3 739 | 61 | 1 141 435 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,6226 | 5 006 | 78 | 9 461 879 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,6226 | 529 | 8 | 1 137 696 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,1300 | 15 148 | 229 | 9 456 873 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,1300 | 1 602 | 24 | 1 137 167 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,1970 | 9 143 | 148 | 9 441 725 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,1970 | 967 | 16 | 1 135 565 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,3475 | 8 671 | 133 | 9 432 582 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,3475 | 917 | 14 | 1 134 598 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,8533 | 2 442 | 41 | 9 423 911 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,8533 | 258 | 4 | 1 133 681 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,3210 | 11 305 | 173 | 9 421 469 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,3210 | 1 195 | 18 | 1 133 423 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,7395 | 5 697 | 95 | 9 410 164 | ||||
| 2017-01-09 | 2017-01-09 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 16,7395 | 603 | 10 | 1 132 228 | ||||
| 2016-11-10 | 2016-11-08 | 4 | Troupin Barbara | AQXP | Stock Option (Right to Buy) | D | 11,77 | 50 000 | 50 000 | |||||
| 2016-10-06 | 3 | Troupin Barbara | AQXP | No securities are benefically owned | D | 0 | ||||||||
| 2016-09-21 | 2016-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 13,1497 | 12 550 | 165 | 1 131 625 | ||||
| 2016-09-21 | 2016-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 12,2500 | 2 476 348 | 30 335 | 9 404 467 | ||||
| 2016-09-21 | 2016-09-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 12,2500 | 294 707 | 3 610 | 1 119 075 | ||||
| 2016-08-05 | 2016-08-03 | 4 | Jenkins Abigail | AQXP | Stock Option (Right to Buy) | D | 8,97 | 50 000 | 50 000 | |||||
| 2016-06-15 | 3 | Jenkins Abigail | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2016-05-11 | 2016-05-09 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 7,73 | 7 500 | 7 500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 7,73 | 7 500 | 7 500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 7,73 | 7 500 | 7 500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 7,73 | 7 500 | 7 500 | |||||
| 2016-05-11 | 2016-05-09 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 7,73 | 7 500 | 7 500 | |||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,1560 | 128 975 | 1 052 | 6 928 119 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,1560 | 14 046 | 115 | 824 368 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,9084 | 185 413 | 1 466 | 6 799 144 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,9084 | 20 192 | 160 | 810 322 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,6993 | 11 840 | 91 | 6 613 731 | ||||
| 2016-03-16 | 2016-03-16 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,6993 | 1 289 | 10 | 790 130 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0257 | 68 132 | 547 | 6 601 891 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0257 | 7 420 | 60 | 788 841 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,8786 | 30 986 | 244 | 6 533 759 | ||||
| 2016-03-16 | 2016-03-15 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 7,8786 | 3 374 | 27 | 781 421 | ||||
| 2016-03-14 | 2016-03-10 | 4 | SHREWSBURY STEPHEN B | AQXP | Stock Option (Right to Buy) | D | 8,08 | 35 000 | 35 000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 8,08 | 120 000 | 120 000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 8,08 | 40 000 | 40 000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 8,08 | 35 000 | 35 000 | |||||
| 2016-03-14 | 2016-03-10 | 4 | Mitchell David Chilton | AQXP | Stock Option (Right to Buy) | D | 8,08 | 25 000 | 25 000 | |||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,9960 | 3 581 | 39 | 6 502 773 | ||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,9960 | 395 | 4 | 778 047 | ||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,8033 | 66 345 | 717 | 6 499 192 | ||||
| 2016-01-26 | 2016-01-26 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,8033 | 7 318 | 79 | 777 652 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11,2043 | 2 522 | 28 | 6 432 847 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11,2043 | 278 | 3 | 770 334 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,9755 | 4 503 | 49 | 6 430 325 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,9755 | 497 | 5 | 770 056 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11,2326 | 2 833 | 32 | 6 425 822 | ||||
| 2016-01-26 | 2016-01-25 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 11,2326 | 312 | 4 | 769 559 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,6908 | 25 650 | 274 | 6 422 989 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,6908 | 2 810 | 30 | 769 247 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,6000 | 156 | 2 | 6 397 339 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,6000 | 17 | 0 | 766 437 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,6937 | 4 021 | 43 | 6 397 183 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,6937 | 440 | 5 | 766 420 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 10,7814 | 17 221 | 186 | 6 393 162 | ||||
| 2016-01-26 | 2016-01-22 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 10,7814 | 1 887 | 20 | 765 980 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9000 | 1 734 | 15 | 6 375 941 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9000 | 190 | 2 | 764 093 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9572 | 27 996 | 251 | 6 374 207 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9572 | 3 067 | 27 | 763 903 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9559 | 13 789 | 123 | 6 346 211 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9559 | 1 511 | 14 | 760 836 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9,8852 | 57 453 | 568 | 6 332 422 | ||||
| 2016-01-20 | 2016-01-20 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9,8852 | 6 294 | 62 | 759 325 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9,1537 | 14 313 | 131 | 6 274 969 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9,1537 | 1 568 | 14 | 753 031 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9,2149 | 10 123 | 93 | 6 260 656 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9,2149 | 1 109 | 10 | 751 463 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 9,0757 | 45 903 | 417 | 6 250 533 | ||||
| 2016-01-20 | 2016-01-19 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 9,0757 | 5 029 | 46 | 750 354 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,5591 | 47 193 | 404 | 6 204 630 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,5591 | 5 196 | 44 | 745 325 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9529 | 4 949 | 44 | 6 157 437 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9529 | 545 | 5 | 740 129 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,8249 | 3 279 | 29 | 6 152 488 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,8249 | 361 | 3 | 739 584 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0999 | 20 851 | 169 | 6 149 209 | ||||
| 2016-01-15 | 2016-01-15 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0999 | 2 296 | 19 | 739 223 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0764 | 2 998 | 24 | 6 128 358 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0764 | 330 | 3 | 736 927 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,9110 | 12 706 | 101 | 6 125 360 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,9110 | 1 399 | 11 | 736 597 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,1717 | 90 550 | 740 | 6 112 654 | ||||
| 2016-01-15 | 2016-01-14 | 4/A | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 8,1717 | 9 970 | 81 | 735 198 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,5591 | 47 193 | 404 | 6 204 630 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,5591 | 5 196 | 44 | 745 325 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9529 | 4 949 | 44 | 6 157 437 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,9529 | 545 | 5 | 740 129 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,8249 | 3 279 | 29 | 6 152 488 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,8249 | 361 | 3 | 739 584 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0999 | 20 851 | 169 | 6 149 209 | ||||
| 2016-01-15 | 2016-01-15 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0999 | 2 296 | 19 | 739 223 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0764 | 2 998 | 24 | 6 128 358 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,0764 | 330 | 3 | 736 927 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,9110 | 12 706 | 101 | 6 125 360 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 7,9110 | 1 399 | 11 | 736 597 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 8,1717 | 90 550 | 740 | 6 112 654 | ||||
| 2016-01-15 | 2016-01-14 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 8,1717 | 9 970 | 81 | 735 198 | ||||
| 2015-12-23 | 3 | McCloskey Shelley | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2015-11-03 | 2015-10-31 | 4 | Bridger Gary | AQXP | Common Stock | I | -1 543 989 | 0 | ||||||
| 2015-09-11 | 2015-09-10 | 4 | BAKER BROS. ADVISORS LP See Footnotes | AQXP | Common Stock | I | 15,5000 | 2 213 469 | 34 309 | 6 022 104 | ||||
| 2015-09-11 | 2015-09-10 | 4 | BAKER BROS. ADVISORS LP | AQXP | Common Stock | I | 15,5000 | 266 563 | 4 132 | 725 228 | ||||
| 2015-08-26 | 2015-08-24 | 4 | Mitchell David Chilton By spouse | AQXP | Common Stock | I | 17,8100 | 3 575 | 64 | 3 575 | ||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 5,76 | 28 075 | 1 872 | |||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 5,76 | 7 812 | 0 | |||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 18,6700 | -35 887 | -670 | 0 | ||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 5,7600 | 28 075 | 162 | 35 887 | ||||
| 2015-08-14 | 2015-08-12 | 4 | MacKenzie Lloyd | AQXP | Common Stock | D | 5,7600 | 7 812 | 45 | 7 812 | ||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 5,76 | -20 833 | 0 | |||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 5,76 | -8 246 | 2 170 | |||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Common Stock | D | 18,6700 | -29 079 | -543 | 0 | ||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Common Stock | D | 5,7600 | 20 833 | 120 | 29 079 | ||||
| 2015-08-14 | 2015-08-12 | 4 | Alam Kamran | AQXP | Common Stock | D | 5,7600 | 8 246 | 47 | 8 246 | ||||
| 2015-08-13 | 2015-08-11 | 4 | Mitchell David Chilton | AQXP | Common Stock | D | 24,3600 | 1 600 | 39 | 1 600 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 23,4112 | -58 632 | -1 373 | 975 403 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 22,5994 | -44 268 | -1 000 | 1 034 035 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 24,3129 | -31 400 | -763 | 1 078 303 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 20,3476 | -25 931 | -528 | 1 109 703 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 26,3213 | -13 109 | -345 | 1 135 634 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 25,3233 | -12 726 | -322 | 1 148 743 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 38,4947 | -11 627 | -448 | 1 161 469 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 36,3687 | -10 544 | -383 | 1 173 096 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 37,2264 | -9 901 | -369 | 1 183 640 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 39,5172 | -9 142 | -361 | 1 193 541 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 21,4506 | -8 969 | -192 | 1 202 683 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 27,3561 | -8 565 | -234 | 1 211 652 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 40,2955 | -6 073 | -245 | 1 220 217 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 35,6072 | -3 207 | -114 | 1 226 290 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 28,4670 | -2 975 | -85 | 1 229 497 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 41,2475 | -2 840 | -117 | 1 232 472 | ||||
| 2015-08-12 | 2015-08-10 | 4 | PFIZER INC | AQXP | Common Stock | D | 29,0000 | -18 | -1 | 1 235 312 | ||||
| 2015-08-12 | 2015-08-11 | 4 | JOHNSON & JOHNSON Johnson & Johnson Innovation - JJDC, Inc. | AQXP | Common Stock | I | 20,7400 | -1 283 366 | -26 617 | 100 000 | ||||
| 2015-08-12 | 2015-08-10 | 4 | JOHNSON & JOHNSON Johnson & Johnson Innovation - JJDC, Inc. | AQXP | Common Stock | I | 31,6600 | -231 455 | -7 328 | 1 383 366 | ||||
| 2015-08-10 | 3/A | BAKER FELIX | AQXP | Common Stock | D | 2 260 | ||||||||
| 2015-08-10 | 3/A | BAKER FELIX | AQXP | Common Stock | D | 2 260 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8 075 935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4 725 965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8 075 935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8 075 935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4 725 965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4 725 965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4 725 965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8 075 935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4 725 965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8 075 935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4 725 965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 4 725 965 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8 075 935 | ||||||||
| 2015-08-10 | 3 | 667, L.P. | AQXP | Common Stock | I | 8 075 935 | ||||||||
| 2015-03-16 | 2015-03-12 | 4 | SHREWSBURY STEPHEN B | AQXP | Stock Option (Right to Buy) | D | 12,03 | 25 000 | 25 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Nolan Sean P. | AQXP | Stock Option (Right to Buy) | D | 12,03 | 10 000 | 10 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 12,03 | 65 000 | 65 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 12,03 | 5 000 | 5 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 12,03 | 5 000 | 5 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 12,03 | 25 000 | 25 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 12,03 | 5 000 | 5 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 12,03 | 5 000 | 5 000 | |||||
| 2015-03-16 | 2015-03-12 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 12,03 | 25 000 | 25 000 | |||||
| 2015-02-09 | 2014-09-02 | 5 | SHREWSBURY STEPHEN B | AQXP | Common Stock | D | 8,2200 | 400 | 3 | 400 | ||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series C Preferred Stock | I | -379 543 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-2 Preferred Stock | I | -292 532 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-1 Preferred Stock | I | -293 884 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-2 Preferred Stock | I | -170 454 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-1 Preferred Stock | I | -255 681 | 0 | ||||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 11,0000 | 272 727 | 3 000 | 1 664 821 | ||||
| 2015-02-03 | 2014-03-12 | 4/A | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 1 392 094 | 1 392 094 | ||||||
| 2015-01-13 | 2015-01-11 | 4 | Mitchell David Chilton | AQXP | Stock Option (Right to Buy) | D | 9,51 | 35 000 | 35 000 | |||||
| 2014-12-18 | 2014-12-17 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,5800 | -1 593 | -12 | 1 342 094 | ||||
| 2014-12-18 | 2014-12-16 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,6300 | -6 507 | -50 | 1 343 687 | ||||
| 2014-12-15 | 2014-12-12 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,5100 | -3 645 | -27 | 1 350 194 | ||||
| 2014-12-15 | 2014-12-11 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,5000 | -1 355 | -10 | 1 353 839 | ||||
| 2014-12-10 | 2014-12-10 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,7000 | -1 300 | -10 | 1 355 194 | ||||
| 2014-12-10 | 2014-12-09 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,7300 | -5 000 | -39 | 1 356 494 | ||||
| 2014-12-10 | 2014-12-08 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,6900 | -2 000 | -15 | 1 361 494 | ||||
| 2014-12-05 | 2014-12-05 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,7800 | -4 200 | -33 | 1 363 494 | ||||
| 2014-12-05 | 2014-12-04 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,7600 | -10 073 | -78 | 1 367 694 | ||||
| 2014-12-05 | 2014-12-03 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,7500 | -1 627 | -13 | 1 377 767 | ||||
| 2014-12-03 | 2014-12-01 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,5400 | -1 200 | -9 | 1 379 394 | ||||
| 2014-11-26 | 2014-11-26 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,6000 | -500 | -4 | 1 380 594 | ||||
| 2014-11-26 | 2014-11-25 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 7,8000 | -1 500 | -12 | 1 381 094 | ||||
| 2014-11-24 | 2014-11-24 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 8,0200 | -4 000 | -32 | 1 382 594 | ||||
| 2014-11-24 | 2014-11-21 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 8,2500 | -2 400 | -20 | 1 386 594 | ||||
| 2014-11-24 | 2014-11-20 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 8,2100 | -3 100 | -25 | 1 388 994 | ||||
| 2014-05-12 | 2014-05-08 | 4 | SHREWSBURY STEPHEN B | AQXP | Stock Option (Right to Buy) | D | 10,10 | 31 250 | 31 250 | |||||
| 2014-05-12 | 2014-05-08 | 4 | Main David | AQXP | Stock Option (Right to Buy) | D | 10,10 | 65 000 | 65 000 | |||||
| 2014-05-12 | 2014-05-08 | 4 | Alam Kamran | AQXP | Stock Option (Right to Buy) | D | 10,10 | 31 250 | 31 250 | |||||
| 2014-05-12 | 2014-05-08 | 4 | MacKenzie Lloyd | AQXP | Stock Option (Right to Buy) | D | 10,10 | 25 000 | 25 000 | |||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Exchangeable Shares | D | -71 530 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Exchangeable Shares | D | 11,0000 | -9 459 | -104 | 0 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Stock | D | 71 530 | 71 530 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Special Voting Stock | D | -71 530 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Main David | AQXP | Common Special Voting Stock | D | 11,0000 | -9 459 | -104 | 71 530 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Exchangeable Shares | D | -378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Preferred Stock | D | -378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Preferred Stock | D | 378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Exchangeable Shares | D | -325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Preferred Stock | D | -325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Preferred Stock | D | 325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Exchangeable Shares | D | -326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Preferred Stock | D | -326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Preferred Stock | D | 326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Preferred Stock | D | -189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Exchangeable Shares | D | -189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Preferred Stock | D | 189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Exchangeable Shares | D | -284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Preferred Stock | D | -284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Preferred Stock | D | 284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Exchangeable Shares | D | -40 147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Exchangeable Shares | D | 11,0000 | 36 502 | 402 | 40 147 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Stock | D | 1 543 989 | 1 543 989 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series C Special Voting Stock | D | -378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Special Voting Stock | D | -325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Special Voting Stock | D | -326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Special Voting Stock | D | -189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Series A-1 Special Voting Stock | D | -284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | -40 147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | 36 502 | 40 147 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Preferred Stock | I | -378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Exchangeable Shares | I | -378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Preferred Stock | I | 378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Preferred Stock | I | -325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Exchangeable Shares | I | -325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Preferred Stock | I | 325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Preferred Stock | I | -326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Exchangeable Shares | I | -326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Preferred Stock | I | 326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Preferred Stock | I | -189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Exchangeable Shares | I | -189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Preferred Stock | I | 189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Exchangeable Shares | I | -284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Preferred Stock | I | -284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Preferred Stock | I | 284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Exchangeable Shares | I | -40 147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Exchangeable Shares | I | 11,0000 | 36 502 | 402 | 40 147 | ||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Stock | I | 1 543 989 | 1 543 989 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series C Special Voting Stock | I | -378 786 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-2 Special Voting Stock | I | -325 035 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series B-1 Special Voting Stock | I | -326 538 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-2 Special Voting Stock | I | -189 393 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Series A-1 Special Voting Stock | I | -284 090 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Special Voting Stock | I | -40 147 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | Bridger Gary See Note | AQXP | Common Special Voting Stock | I | 36 502 | 40 147 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Series C Preferred Stock | D | -301 005 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Series B-2 Preferred Stock | D | -327 178 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Series B-1 Preferred Stock | D | -334 420 | 0 | ||||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Common Stock | D | 11,0000 | 272 727 | 3 000 | 1 235 330 | ||||
| 2014-03-14 | 2014-03-12 | 4 | PFIZER INC | AQXP | Common Stock | D | 962 603 | 962 603 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series C Preferred Stock | I | -379 543 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-2 Preferred Stock | I | -292 532 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series B-1 Preferred Stock | I | -293 884 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-2 Preferred Stock | I | -170 454 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON By Johnson & Johnson Development Corporation | AQXP | Series A-1 Preferred Stock | I | -255 681 | 0 | ||||||
| 2014-03-12 | 2014-03-12 | 4 | JOHNSON & JOHNSON Johnson & Johnson Development Corporation | AQXP | Common Stock | I | 1 392 094 | 1 392 094 | ||||||
| 2014-03-10 | 2014-03-06 | 4 | SIMPSON TODD E | AQXP | Stock Option (Right to Buy) | D | 11,00 | 8 333 | 8 333 | |||||
| 2014-03-10 | 2014-03-06 | 4 | Pelzer Robert | AQXP | Stock Option (Right to Buy) | D | 11,00 | 8 333 | 14 843 | |||||
| 2014-03-10 | 2014-03-06 | 4 | LEVITT DANIEL J | AQXP | Stock Option (Right to Buy) | D | 11,00 | 8 333 | 20 051 | |||||
| 2014-03-10 | 2014-03-06 | 4 | Bridger Gary | AQXP | Stock Option (Right to Buy) | D | 11,00 | 8 333 | 8 333 | |||||
| 2014-03-06 | 3 | Jones Elaine V | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2014-03-06 | 3 | SIMPSON TODD E | AQXP | No securities are beneficially owned | D | 0 | ||||||||
| 2014-03-06 | 3 | Main David | AQXP | Common Special Voting Stock | D | 161 978 | ||||||||
| 2014-03-06 | 3 | Main David | AQXP | Common Special Voting Stock | D | 161 978 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | 1 511 132 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A- Special Voting Stock | D | 1 791 577 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Special Voting Stock | D | 1 696 880 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Special Voting Stock | D | 1 834 025 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Special Voting Stock | D | 1 832 522 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Common Special Voting Stock | D | 1 511 132 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A- Special Voting Stock | D | 1 791 577 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series A-2 Special Voting Stock | D | 1 696 880 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-1 Special Voting Stock | D | 1 834 025 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series B-2 Special Voting Stock | D | 1 832 522 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series C Special Voting Stock | D | 1 886 273 | ||||||||
| 2014-03-06 | 3 | Ventures West 8 Limited Partnership | AQXP | Series C Special Voting Stock | D | 1 886 273 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series C Special Voting Stock | I | 1 886 273 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series C Special Voting Stock | I | 1 886 273 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-2 Special Voting Stock | I | 1 832 522 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-1 Special Voting Stock | I | 1 834 025 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-1 Special Voting Stock | I | 1 791 577 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Common Special Voting Stock | I | 1 511 132 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-2 Special Voting Stock | I | 1 696 880 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-2 Special Voting Stock | I | 1 696 880 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series A-1 Special Voting Stock | I | 1 791 577 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Common Special Voting Stock | I | 1 511 132 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-1 Special Voting Stock | I | 1 834 025 | ||||||||
| 2014-03-06 | 3 | Bridger Gary See Note (9) | AQXP | Series B-2 Special Voting Stock | I | 1 832 522 |
P
Otwarty rynek lub prywatny zakup niepochodnych lub pochodnych papierów wartościowych
S
Otwarty rynek lub prywatna sprzedaż niepochodnych lub pochodnych papierów wartościowych
A
Grant, nagroda lub inne nabycie papierów wartościowych od spółki (np. opcja)
C
Konwersja instrumentu pochodnego
D
Sprzedaż lub przeniesienie papierów wartościowych z powrotem do spółki
F
Zapłata ceny wykonania lub zobowiązania podatkowego z wykorzystaniem części papierów wartościowych otrzymanych od spółki
G
Darowizna papierów wartościowych przez lub na rzecz insidera
K
Swapy kapitałowe i podobne transakcje zabezpieczające
M
Wykonanie lub konwersja pochodnego papieru wartościowego otrzymanego od spółki (takiego jak opcja)
V
Transakcja dobrowolnie zgłoszona na Formularzu 4
J
Inne (wraz z przypisem opisującym transakcję)
