Tango Therapeutics, Inc.
US ˙ NasdaqGM ˙ US87583X1090

SecurityTNGX / Tango Therapeutics, Inc.
InstitutionVanguard Group Inc
Latest Disclosed Ownership0 shares
Ownership 0.00%
Vanguard Group Inc ownership in TNGX / Tango Therapeutics, Inc.

2026-03-27 - Vanguard Group Inc has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 0 shares of Tango Therapeutics, Inc. (US:TNGX). This represents 0.0 percent ownership of the company. In their previous filing dated 2026-01-30 , Vanguard Group Inc had reported owning 6,750,977 shares, indicating a decrease of -100.00 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date		Effective
Date		Form Prev
Shares		 Latest
Shares		 ΔShares
(Percent)		 Ownership
(Percent)		 ΔOwnership
(Percent)
2026-03-27 2026-03-27 13G/A 6,750,977 0 -100.00 0.00 -100.00
2026-01-30 2026-01-30 13G 6,750,977 5.01

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-01-29 2025-12-31 13F TANGO THERAPEUTICS COM 87583X109 6,750,977 1,698,974 33.63 59,814 40.95 0.0009
2025-11-07 2025-09-30 13F TANGO THERAPEUTICS COM 87583X109 5,052,003 1,025,203 25.46 42,437 105.83 0.0006
2025-08-11 2025-06-30 13F TANGO THERAPEUTICS COM 87583X109 4,026,800 151,255 3.90 20,617 288.34 0.0003
2025-05-09 2025-03-31 13F TANGO THERAPEUTICS COM 87583X109 3,875,545 -109,680 -2.75 5,309 -56.89 0.0001
2025-02-11 2024-12-31 13F TANGO THERAPEUTICS COM 87583X109 3,985,225 339,922 9.32 12,314 -56.13 0.0002
2024-11-13 2024-09-30 13F TANGO THERAPEUTICS COM 87583X109 3,645,303 350,731 10.65 28,069 -0.70 0.0005
2024-08-13 2024-06-30 13F TANGO THERAPEUTICS COM 87583X109 3,294,572 213,687 6.94 28,267 15.55 0.0005
2024-05-10 2024-03-31 13F TANGO THERAPEUTICS COM 87583X109 3,080,885 101,673 3.41 24,462 -17.06 0.0005
2024-03-11 2023-12-31 13F/A-1 TANGO THERAPEUTICS COM 87583X109 2,979,212 39,369 1.34 29,494 -10.90 0.0006
2024-02-14 2023-12-31 13F TANGO THERAPEUTICS COM 87583X109 2,979,212 39,369 29,494 0.0006
2023-12-18 2023-09-30 13F/A-1 TANGO THERAPEUTICS COM 87583X109 2,939,843 197,624 7.21 33,103 263.60 0.0008
2023-11-14 2023-09-30 13F TANGO THERAPEUTICS COM 87583X109 2,939,843 197,624 33,103 0.0001
2023-08-14 2023-06-30 13F TANGO THERAPEUTICS COM 87583X109 2,742,219 -7,703 -0.28 9,104 -16.18 0.0002
2023-07-14 2023-03-31 13F/A-1 TANGO THERAPEUTICS COM 87583X109 2,749,922 35,110 1.29 10,862 -44.81 0.0003
2023-05-15 2023-03-31 13F TANGO THERAPEUTICS COM 87583X109 2,749,922 35,110 10,862 0.0001
2023-02-10 2022-12-31 13F TANGO THERAPEUTICS COM 87583X109 2,714,812 111,068 4.27 19,682 108.81 0.0005
2022-11-14 2022-09-30 13F TANGO THERAPEUTICS COM 87583X109 2,603,744 -408,174 -13.55 9,426 -30.91 0.0003
2022-08-12 2022-06-30 13F TANGO THERAPEUTICS COM 87583X109 3,011,918 297,955 10.98 13,644 -33.67 0.0004
2022-05-13 2022-03-31 13F TANGO THERAPEUTICS COM 87583X109 2,713,963 1,267,198 87.59 20,571 29.96 0.0005
2022-02-14 2021-12-31 13F TANGO THERAPEUTICS COM 87583X109 1,446,765 61,939 4.47 15,829 -11.60 0.0004
2021-11-12 2021-09-30 13F TANGO THERAPEUTICS COM 87583X109 1,384,826 1,384,826 17,906 0.0004
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.