Disc Medicine, Inc.
US ˙ NasdaqGM ˙ US2546041011

SecurityIRON / Disc Medicine, Inc.
InstitutionJanus Henderson Group Plc
Latest Disclosed Ownership11,555 shares
Latest Disclosed Value $ 739,462
Janus Henderson Group Plc ownership in IRON / Disc Medicine, Inc.

On May 18, 2026 - Janus Henderson Group Plc filed a 13F-HR/A form disclosing ownership of 11,555 shares of Disc Medicine, Inc. (US:IRON) valued at $738,827 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 11,555 shares of Disc Medicine, Inc.. This represents a change in shares of 0.00% during the quarter. The current value of the position is $821,676 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-18 2026-03-31 13F/A-1 DISC MEDICINE COM 254604101 11,555 0 0.00 739 -19.41 0.0001
2026-05-15 2026-03-31 13F DISC MEDICINE COM 254604101 11,555 0 0.00 739 -19.41 0.0001
2026-02-17 2025-12-31 13F DISC MEDICINE COM 254604101 11,555 -350,149 -96.81 918 -96.16 0.0004
2025-11-14 2025-09-30 13F DISC MEDICINE COM 254604101 361,704 -1,192,257 -76.72 23,901 -70.94 0.0109
2025-08-14 2025-06-30 13F DISC MEDICINE COM 254604101 1,553,961 130,702 9.18 82,250 10.47 0.0403
2025-05-15 2025-03-31 13F DISC MEDICINE COM 254604101 1,423,259 205,444 16.87 74,452 -3.52 0.0408
2025-02-14 2024-12-31 13F DISC MEDICINE COM 254604101 1,217,815 467,988 62.41 77,170 109.55 0.0392
2024-11-14 2024-09-30 13F DISC MEDICINE COM 254604101 749,827 303,954 68.17 36,828 83.57 0.0188
2024-08-14 2024-06-30 13F DISC MEDICINE COM 254604101 445,873 -75,900 -14.55 20,062 -38.20 0.0107
2024-05-15 2024-03-31 13F DISC MEDICINE COM 254604101 521,773 78,595 17.73 32,465 26.82 0.0177
2024-02-14 2023-12-31 13F DISC MEDICINE COM 254604101 443,178 -57,202 -11.43 25,600 8.90 0.0153
2023-11-14 2023-09-30 13F DISC MEDICINE COM 254604101 500,380 1 0.00 23,508 5.81 0.0154
2023-08-14 2023-06-30 13F DISC MEDICINE COM 254604101 500,379 456,681 1,045.08 22,217 2,301.73 0.0138
2023-05-15 2023-03-31 13F DISC MEDICINE COM 254604101 43,698 -456,632 -91.27 926 -5.71 0.0006
2023-02-14 2022-12-31 13F DISC MEDICINE COM 254604101 500,330 500,330 982 0.0007
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.