Eli Lilly and Company
MX ˙ BMV ˙ US5324571083
SecurityMX:LLY / Eli Lilly and Company
InstitutionComerica Bank
Latest Disclosed Ownership1,485,360 shares
Latest Disclosed Value $ 1,596,286,410
Comerica Bank reports 0.63% decrease in ownership of LLY / Eli Lilly and Company

On January 29, 2026 - Comerica Bank filed a 13F-HR form disclosing ownership of 1,485,360 shares of Eli Lilly and Company (MX:LLY) valued at $1,596,286,410 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2025 disclosing 1,494,762 shares of Eli Lilly and Company. This represents a change in shares of -0.63% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-01-29 2025-12-31 13F ELI LILLY COM 532457108 1,485,360 -9,402 -0.63 1,596,286 39.96 6.3687
2025-11-14 2025-09-30 13F ELI LILLY COM 532457108 1,494,762 -7,898 -0.53 1,140,503 -2.63 4.2901
2025-08-14 2025-06-30 13F ELI LILLY COM 532457108 1,502,660 1,580 0.11 1,171,368 -5.52 4.5463
2025-05-14 2025-03-31 13F ELI LILLY COM 532457108 1,501,080 -2,583 -0.17 1,239,757 6.80 5.2065
2025-02-14 2024-12-31 13F/A-1 ELI LILLY COM 532457108 1,503,663 -7,957 -0.53 1,160,828 -13.32 4.6813
2025-02-14 2024-12-31 13F ELI LILLY COM 532457108 1,503,663 -7,957 1,160,828 3.8881
2024-11-14 2024-09-30 13F ELI LILLY COM 532457108 1,511,620 -1,363 -0.09 1,339,205 -2.24 5.2970
2024-08-15 2024-06-30 13F LILLY ELI COMMON 532457108 1,512,983 631,312 71.60 1,369,825 99.71 5.7010
2024-05-16 2024-03-31 13F LILLY ELI COMMON 532457108 881,671 -5,453 -0.61 685,905 32.64 2.9558
2024-02-14 2023-12-31 13F LILLY ELI COMMON 532457108 887,124 243,366 37.80 517,122 49.55 2.3817
2023-11-21 2023-09-30 13F ELI LILLY COMMON 532457108 643,758 643,758 345,781 1.8009
2023-08-22 2023-06-30 13F LILLY ELI EQU 532457108 0 -162,609 -100.00 0 -100.00
2023-01-26 2022-12-31 13F LILLY ELI COM 532457108 162,609 8,328 5.40 58 -99.89 0.4522
2022-10-28 2022-09-30 13F LILLY ELI COM 532457108 154,281 -3,073 -1.95 53,675 4.57 0.4525
2022-08-02 2022-06-30 13F LILLY ELI COM 532457108 157,354 25,209 19.08 51,329 32.61 0.4215
2022-04-27 2022-03-31 13F LILLY ELI COM 532457108 132,145 -348 -0.26 38,708 22.00 0.2809
2022-02-18 2021-12-31 13F LILLY ELI COM 532457108 132,493 1,854 1.42 31,727 -0.36 0.2335
2021-11-22 2021-09-30 13F LILLY ELI COM 532457108 130,639 -35,364 -21.30 31,843 -29.06 0.1918
2021-08-26 2021-06-30 13F LILLY ELI COM 532457108 166,003 -2,846 -1.69 44,888 40.87 0.2680
2021-04-28 2021-03-31 13F LILLY ELI COM 532457108 168,849 -18,934 -10.08 31,865 -17.68 0.1900
2021-01-28 2020-12-31 13F LILLY ELI COM 532457108 187,783 -8,023 -4.10 38,710 38.85 0.2456
2020-10-30 2020-09-30 13F LILLY ELI COM 532457108 195,806 -12,939 -6.20 27,879 -18.98 0.2024
2020-07-31 2020-06-30 13F LILLY ELI COM 532457108 208,745 18,559 9.76 34,409 11.05 0.2651
2020-05-01 2020-03-31 13F LILLY ELI COM 532457108 190,186 -6,824 -3.46 30,986 10.24 0.2842
2020-02-07 2019-12-31 13F LILLY ELI COM 532457108 197,010 -4,261 -2.12 28,108 29.50 0.2129
2019-10-31 2019-09-30 13F LILLY ELI COM 532457108 201,271 -2,025 -1.00 21,705 -0.30 0.1715
2019-08-02 2019-06-30 13F LILLY ELI COM 532457108 203,296 -4,705 -2.26 21,770 -17.71 0.1743
2019-05-02 2019-03-31 13F LILLY ELI COM 532457108 208,001 -31,183 -13.04 26,456 -4.41 0.2145
2019-02-06 2018-12-31 13F LILLY ELI COM 532457108 239,184 4,344 1.85 27,676 6.76 0.2351
2018-11-01 2018-09-30 13F LILLY ELI COM 532457108 234,840 -53,882 -18.66 25,923 0.24 0.2091
2018-08-01 2018-06-30 13F LILLY ELI COM 532457108 288,722 14,954 5.46 25,861 18.45 0.1808
2018-05-01 2018-03-31 13F LILLY ELI COM 532457108 273,768 -28,369 -9.39 21,833 -14.28 0.1560
2018-02-02 2017-12-31 13F LILLY ELI COM 532457108 302,137 -731 -0.24 25,470 1.75 0.1697
2017-11-06 2017-09-30 13F LILLY ELI COM 532457108 302,868 -99 -0.03 25,032 -2.50 0.1811
2017-08-03 2017-06-30 13F LILLY ELI COM 532457108 302,967 -13 -0.00 25,673 4.18 0.1921
2017-05-03 2017-03-31 13F LILLY ELI COM 532457108 302,980 -445 -0.15 24,642 4.93 0.1870
2017-02-08 2016-12-31 13F LILLY ELI COM 532457108 303,425 9,702 3.30 23,484 -1.90 0.1858
2016-08-11 2016-06-30 13F LILLY ELI COM 532457108 293,723 -14,351 -4.66 23,938 2.88 0.2068
2016-05-11 2016-03-31 13F LILLY ELI COM 532457108 308,074 5,996 1.98 23,269 -5.19 0.2078
2016-02-05 2015-12-31 13F LILLY ELI COM 532457108 302,078 -2,044 -0.67 24,544 -3.57 0.2408
2015-11-12 2015-09-30 13F LILLY ELI COM 532457108 304,122 -353,772 -53.77 25,452 -53.66 0.2410
2015-08-13 2015-06-30 13F LILLY ELI COM 532457108 657,894 339,454 106.60 54,928 137.43 0.2358
2015-05-15 2015-03-31 13F LILLY ELI COM 532457108 318,440 -300,094 -48.52 23,134 -45.79 0.1959
2015-02-13 2014-12-31 13F LILLY ELI COM 532457108 618,534 338,854 121.16 42,672 135.26 0.1845
2014-10-21 2014-09-30 13F LILLY ELI COM 532457108 279,680 -13,601 -4.64 18,138 -0.52 0.1602
2014-08-12 2014-06-30 13F LILLY ELI COM 532457108 293,281 -89,584 -23.40 18,233 -19.09 0.1550
2014-05-15 2014-03-31 13F LILLY ELI COM 532457108 382,865 -146,610 -27.69 22,535 -16.55 0.1726
2014-02-11 2013-12-31 13F LILLY ELI COM 532457108 529,475 -88,644 -14.34 27,003 -13.20 0.2093
2013-11-12 2013-09-30 13F LILLY ELI COM 532457108 618,119 -19,710 -3.09 31,110 -0.70 0.2165
2013-08-13 2013-06-30 13F/A-1 LILLY ELI COM 532457108 637,829 637,829 31,329 0.2554
2013-08-08 2013-06-30 13F LILLY ELI COM 532457108 4,557,065 223,837
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.