Ionis Pharmaceuticals, Inc.
MX ˙ BMV ˙ US4622221004
SecurityMX:IONS / Ionis Pharmaceuticals, Inc.
InstitutionBessemer Group Inc
Latest Disclosed Ownership94 shares
Latest Disclosed Value $ 7
Bessemer Group Inc reports 29.32% decrease in ownership of IONS / Ionis Pharmaceuticals, Inc.

On May 6, 2026 - Bessemer Group Inc filed a 13F-HR form disclosing ownership of 94 shares of Ionis Pharmaceuticals, Inc. (MX:IONS) valued at $7 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 5, 2026 disclosing 133 shares of Ionis Pharmaceuticals, Inc..

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-06 2026-03-31 13F IONIS PHARMACEUTICALS SC 462222100 94 -39 -29.32 0 0.0000
2026-02-05 2025-12-31 13F IONIS PHARMACEUTICALS SC 462222100 133 0 0.00 0 0.0000
2025-11-05 2025-09-30 13F IONIS PHARMACEUTICALS SC 462222100 133 94 241.03 0 0.0000
2025-08-01 2025-06-30 13F IONIS PHARMACEUTICALS SC 462222100 39 -34 -46.58 0 0.0000
2025-04-23 2025-03-31 13F IONIS PHARMACEUTICALS SC 462222100 73 73 0 0.0000
2024-11-12 2024-09-30 13F IONIS PHARMACEUTICALS SC 462222100 0 -52 -100.00 0 0.0000
2024-08-13 2024-06-30 13F IONIS PHARMACEUTICALS SC 462222100 52 0 0.00 0 0.0000
2024-08-13 2024-03-31 13F/A-1 IONIS PHARMACEUTICALS SC 462222100 52 0 0.00 0 0.0000
2024-05-13 2024-03-31 13F IONIS PHARMACEUTICALS SC 462222100 52 0 0 0.0000
2024-02-09 2023-12-31 13F IONIS PHARMACEUTICALS SC 462222100 52 0 0.00 0 0.0000
2023-11-13 2023-09-30 13F IONIS PHARMACEUTICALS SC 462222100 52 0 0.00 0 0.0000
2023-08-10 2023-06-30 13F IONIS PHARMACEUTICALS SC 462222100 52 0 0.00 0 0.0000
2023-05-10 2023-03-31 13F IONIS PHARMACEUTICALS SC 462222100 52 27 108.00 0 0.0000
2023-02-13 2022-12-31 13F IONIS PHARMACEUTICALS SC 462222100 25 25 0 0.0000
2022-08-10 2022-06-30 13F IONIS PHARMACEUTICALS SC 462222100 0 -900 -100.00 0 -100.00
2022-05-12 2022-03-31 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 33 22.22 0.0001
2022-01-27 2021-12-31 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 27 -10.00 0.0001
2021-11-12 2021-09-30 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 30 -16.67 0.0001
2021-08-06 2021-06-30 13F IONIS PHARMACEUTICALS SC 462222100 900 -129 -12.54 36 -21.74 0.0001
2021-05-13 2021-03-31 13F IONIS PHARMACEUTICALS SC 462222100 1,029 129 14.33 46 -9.80 0.0001
2021-02-09 2020-12-31 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 51 18.60 0.0001
2020-11-12 2020-09-30 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 43 -18.87 0.0001
2020-08-05 2020-06-30 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 53 23.26 0.0002
2020-04-30 2020-03-31 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 43 -20.37 0.0002
2020-02-04 2019-12-31 13F IONIS PHARMACEUTICALS SC 462222100 900 -50 -5.26 54 -5.26 0.0002
2019-11-07 2019-09-30 13F IONIS PHARMACEUTICALS SC 462222100 950 0 0.00 57 -6.56 0.0002
2019-07-19 2019-06-30 13F IONIS PHARMACEUTICALS SC 462222100 950 50 5.56 61 -16.44 0.0002
2019-05-13 2019-03-31 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 73 48.98 0.0003
2019-05-21 2018-12-31 13F/A-1 IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 49 6.52 0.0002
2019-02-12 2018-12-31 13F IONIS PHARMACEUTICALS SC 462222100 900 0 49 0.0002
2018-11-06 2018-09-30 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 46 21.05 0.0002
2018-07-25 2018-06-30 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 38 -5.00 0.0001
2018-05-10 2018-03-31 13F IONIS PHARMACEUTICALS SC 462222100 900 -342 -27.54 40 -35.48 0.0002
2018-01-30 2017-12-31 13F IONIS PHARMACEUTICALS SC 462222100 1,242 0 0.00 62 -1.59 0.0002
2017-11-03 2017-09-30 13F IONIS PHARMACEUTICALS SC 462222100 1,242 0 0.00 63 0.00 0.0003
2017-07-27 2017-06-30 13F IONIS PHARMACEUTICALS SC 462222100 1,242 -6,076 -83.03 63 -78.57 0.0003
2017-05-12 2017-03-31 13F IONIS PHARMACEUTICALS SC 462222100 7,318 6,418 713.11 294 583.72 0.0012
2017-02-07 2016-12-31 13F IONIS PHARMACEUTICALS SC 462222100 900 0 0.00 43 30.30 0.0002
2016-11-10 2016-09-30 13F IONIS PHARMACEUTICALS SC 462222100 900 -947 -51.27 33 -23.26 0.0002
2016-08-11 2016-06-30 13F IONIS PHARMACEUTICALS SC 462222100 1,847 211 12.90 43 -34.85 0.0002
2016-05-11 2016-03-31 13F IONIS PHARMACEUTICALS SC 462222100 1,636 579 54.78 66 0.00 0.0004
2016-02-12 2015-12-31 13F IONIS PHARMACEUTICALS SC 462222100 1,057 134 14.52 66 78.38 0.0004
2015-11-16 2015-09-30 13F ISIS PHARMACEUTICALS SC 464330109 923 -116 -11.16 37 -38.33 0.0002
2015-08-14 2015-06-30 13F ISIS PHARMACEUTICALS SC 464330109 1,039 139 15.44 60 5.26 0.0003
2015-06-18 2015-03-31 13F/A-1 ISIS PHARMACEUTICALS SC 464330109 900 300 50.00 57 54.05 0.0003
2015-05-14 2015-03-31 13F ISIS PHARMACEUTICALS SC 464330109 900 57
2015-02-17 2014-12-31 13F ISIS PHARMACEUTICALS SC 464330109 600 0 0.00 37 60.87 0.0002
2014-12-11 2014-09-30 13F/A-1 ISIS PHARMACEUTICALS SC 464330109 600 337 128.14 23 155.56 0.0001
2014-11-13 2014-09-30 13F ISIS PHARMACEUTICALS SC 464330109 600 337 23 0.0001
2014-08-13 2014-06-30 13F ISIS PHARMACEUTICALS SC 464330109 263 -497 -65.39 9 -72.73 0.0001
2014-05-14 2014-03-31 13F ISIS PHARMACEUTICALS SC 464330109 760 630 484.62 33 560.00 0.0002
2014-02-18 2013-12-31 13F ISIS PHARMACEUTICALS SC 464330109 130 0 0.00 5 0.00 0.0000
2013-11-08 2013-09-30 13F ISIS PHARMACEUTICALS SC 464330109 130 130 5 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.