Incyte Corporation
MX ˙ BMV ˙ US45337C1027
SecurityMX:INCY / Incyte Corporation
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership3,651,532 shares
Latest Disclosed Value $ 343,682,192
Renaissance Technologies Llc reports 8.21% decrease in ownership of INCY / Incyte Corporation

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 3,651,532 shares of Incyte Corporation (MX:INCY) valued at $343,682,192 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 3,978,332 shares of Incyte Corporation. This represents a change in shares of -8.21% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F INCYTE COM 45337C102 3,651,532 -326,800 -8.21 343,682 -12.54 0.5376
2026-02-12 2025-12-31 13F INCYTE COM 45337C102 3,978,332 -549,800 -12.14 392,940 2.32 0.6096
2025-11-13 2025-09-30 13F INCYTE COM 45337C102 4,528,132 646,200 16.65 384,031 45.27 0.5070
2025-08-13 2025-06-30 13F INCYTE COM 45337C102 3,881,932 173,200 4.67 264,360 17.72 0.3517
2025-05-14 2025-03-31 13F INCYTE COM 45337C102 3,708,732 -377,200 -9.23 224,564 -20.43 0.3399
2025-02-13 2024-12-31 13F INCYTE COM 45337C102 4,085,932 -413,608 -9.19 282,215 -5.11 0.4178
2024-11-13 2024-09-30 13F INCYTE COM 45337C102 4,499,540 -718,797 -13.77 297,420 -5.98 0.4473
2024-08-09 2024-06-30 13F INCYTE COM 45337C102 5,218,337 -458,100 -8.07 316,336 97,836.53 0.5365
2024-05-13 2024-03-31 13F INCYTE COM 45337C102 5,676,437 122,500 2.21 323 -7.18 0.5083
2024-02-13 2023-12-31 13F INCYTE COM 45337C102 5,553,937 757,404 15.79 349 25.63 0.5398
2023-11-14 2023-09-30 13F INCYTE COM 45337C102 4,796,533 -31,656 -0.66 277 -7.67 0.4724
2023-08-11 2023-06-30 13F INCYTE COM 45337C102 4,828,189 -774,244 -13.82 301 -25.74 0.4332
2023-05-12 2023-03-31 13F INCYTE COM 45337C102 5,602,433 1,034,200 22.64 405 10.38 0.5373
2023-02-13 2022-12-31 13F INCYTE COM 45337C102 4,568,233 -279,000 -5.76 367 -99.89 0.5020
2022-11-14 2022-09-30 13F INCYTE COM 45337C102 4,847,233 -295,500 -5.75 323,020 -17.32 0.4570
2022-08-12 2022-06-30 13F INCYTE COM 45337C102 5,142,733 445,100 9.47 390,693 4.72 0.4625
2022-05-13 2022-03-31 13F INCYTE COM 45337C102 4,697,633 106,900 2.33 373,086 10.72 0.4378
2022-02-11 2021-12-31 13F INCYTE COM 45337C102 4,590,733 179,500 4.07 336,960 11.06 0.4192
2021-11-12 2021-09-30 13F INCYTE COM 45337C102 4,411,233 -103,900 -2.30 303,405 -20.13 0.3919
2021-08-13 2021-06-30 13F INCYTE COM 45337C102 4,515,133 -383,600 -7.83 379,858 -4.59 0.4742
2021-05-13 2021-03-31 13F INCYTE COM 45337C102 4,898,733 -990,400 -16.82 398,120 -22.28 0.4953
2021-02-10 2020-12-31 13F INCYTE COM 45337C102 5,889,133 -316,217 -5.10 512,237 -8.01 0.5562
2020-11-13 2020-09-30 13F INCYTE COM 45337C102 6,205,350 -66,000 -1.05 556,868 -14.59 0.5560
2020-08-13 2020-06-30 13F INCYTE COM 45337C102 6,271,350 1,669,090 36.27 652,032 93.47 0.5629
2020-05-14 2020-03-31 13F INCYTE COM 45337C102 4,602,260 1,001,257 27.80 337,023 7.18 0.3273
2020-02-13 2019-12-31 13F INCYTE COM 45337C102 3,601,003 857,383 31.25 314,440 54.40 0.2416
2019-11-13 2019-09-30 13F INCYTE COM 45337C102 2,743,620 781,310 39.82 203,659 22.16 0.1724
2019-08-12 2019-06-30 13F INCYTE COM 45337C102 1,962,310 1,121,310 133.33 166,718 130.48 0.1468
2019-05-14 2019-03-31 13F INCYTE COM 45337C102 841,000 744,600 772.41 72,334 1,080.00 0.0658
2019-02-12 2018-12-31 13F INCYTE COM 45337C102 96,400 -503,600 -83.93 6,130 -85.21 0.0067
2018-11-13 2018-09-30 13F INCYTE COM 45337C102 600,000 -14,500 -2.36 41,448 0.67 0.0426
2018-08-13 2018-06-30 13F/A-1 INCYTE COM 45337C102 614,500 -306,100 -33.25 41,172 -46.33 0.0449
2018-08-13 2018-06-30 13F INCYTE COM 45337C102 920,600 76,714
2018-05-14 2018-03-31 13F INCYTE COM 45337C102 920,600 164,200 21.71 76,714 7.08 0.0839
2018-02-13 2017-12-31 13F INCYTE COM 45337C102 756,400 756,400 71,639 0.0790
2017-02-13 2016-12-31 13F INCYTE COM 45337C102 0 -62,900 -100.00 0 -100.00
2016-11-14 2016-09-30 13F INCYTE COM 45337C102 62,900 -101,667 -61.78 5,931 -54.94 0.0105
2016-08-12 2016-06-30 13F INCYTE COM 45337C102 164,567 -139,433 -45.87 13,162 -40.26 0.0251
2016-05-13 2016-03-31 13F INCYTE COM 45337C102 304,000 304,000 0.00 22,031 0.0419
2016-02-11 2015-12-31 13F INCYTE COM 45337C102 0 -33,200 -100.00 0 -100.00
2015-11-12 2015-09-30 13F INCYTE COM 45337C102 33,200 -241,800 -87.93 3,663 -87.22 0.0087
2015-08-14 2015-06-30 13F INCYTE COM 45337C102 275,000 275,000 0.00 28,658 0.0653
2015-05-13 2015-03-31 13F INCYTE COM 45337C102 0 -244,800 -100.00 0 -100.00
2015-02-13 2014-12-31 13F INCYTE COM 45337C102 244,800 146,884 150.01 17,897 272.62 0.0432
2014-11-12 2014-09-30 13F INCYTE COM 45337C102 97,916 97,916 119.05 4,803 181.70 0.0132
2014-02-14 2013-12-31 13F INCYTE COM 45337C102 0 -44,700 -100.00 0 -100.00
2013-11-13 2013-09-30 13F INCYTE COM 45337C102 44,700 -58,100 -56.52 1,705 -24.62 0.0041
2013-08-12 2013-06-30 13F INCYTE COM 45337C102 102,800 102,800 2,262 0.0059
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.