Guardant Health, Inc.
MX ˙ BMV ˙ US40131M1099
SecurityMX:GH / Guardant Health, Inc.
InstitutionRathbone Brothers plc
Latest Disclosed Ownership166,507 shares
Latest Disclosed Value $ 15,380,251
Rathbone Brothers plc reports 18.82% decrease in ownership of GH / Guardant Health, Inc.

On May 12, 2026 - Rathbone Brothers plc filed a 13F-HR form disclosing ownership of 166,507 shares of Guardant Health, Inc. (MX:GH) valued at $15,380,251 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on February 6, 2026 disclosing 205,113 shares of Guardant Health, Inc.. This represents a change in shares of -18.82% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-12 2026-03-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 166,507 -38,606 -18.82 15,380 -26.59 0.0657
2026-02-06 2025-12-31 13F/A-1 GUARDANT HEALTH INC USD0.00001 COM 40131M109 205,113 5,025 2.51 20,950 67.59 0.0829
2026-01-21 2025-12-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 205,113 5,025 20,950 0.0829
2025-11-13 2025-09-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 200,088 -5,877 -2.85 12,501 16.64 0.0508
2025-08-07 2025-06-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 205,965 3,838 1.90 10,718 24.48 0.0462
2025-05-13 2025-03-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 202,127 3,166 1.59 8,611 41.66 0.0416
2025-02-13 2024-12-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 198,961 12,375 6.63 6,078 42.01 0.0294
2024-11-13 2024-09-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 186,586 78,191 72.14 4,280 36.74 0.0216
2024-08-09 2024-06-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 108,395 4,667 4.50 3,130 46.33 0.0171
2024-05-14 2024-03-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 103,728 8,050 8.41 2,140 -17.35 0.0123
2024-02-13 2023-12-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 95,678 -1,106 -1.14 2,588 -9.76 0.0167
2023-11-13 2023-09-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 96,784 2,347 2.49 2,869 -15.15 0.0208
2023-08-04 2023-06-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 94,437 -963 -1.01 3,381 51.16 0.0316
2023-05-12 2023-03-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 95,400 -3,119 -3.17 2,236 -16.54 0.0229
2023-02-14 2022-12-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 98,519 -7,563 -7.13 2,680 -53.08 0.0302
2022-11-14 2022-09-30 13F/A-1 GUARDANT HEALTH INC USD0.00001 COM 40131M109 106,082 242 0.23 5,710 33.72 0.0704
2022-11-03 2022-09-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 106,082 242 5,710 0.0704
2022-08-12 2022-06-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 105,840 -51 -0.05 4,270 -39.12 0.0489
2022-05-11 2022-03-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 105,891 -387 -0.36 7,014 -34.02 0.0716
2022-02-10 2021-12-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 106,278 11,271 11.86 10,630 -10.50 0.1033
2021-11-04 2021-09-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 95,007 17,156 22.04 11,877 22.85 0.1278
2021-07-30 2021-06-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 77,851 16,633 27.17 9,668 3.46 0.1074
2021-05-14 2021-03-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 61,218 23,513 62.36 9,345 92.32 0.1197
2021-02-11 2020-12-31 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 37,705 17,458 86.23 4,859 114.71 0.0690
2020-11-13 2020-09-30 13F GUARDANT HEALTH INC USD0.00001 COM 40131M109 20,247 20,247 2,263 0.0387
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.