| Akcje insidera | 73 845 677 shares |
Wynik sentymentu insiderów
Ocena sentymentu insiderów pokazuje firmy, które są kupowane przez insiderów korporacyjnych.
Jest to wynik zaawansowanego, wieloczynnikowego modelu ilościowego, który identyfikuje spółki o najwyższym poziomie akumulacji informacji poufnych. Model rankingowy wykorzystuje kombinację liczby netto insiderów kupujących w ciągu ostatnich 90 dni, całkowitej liczby akcji kupionych jako procent akcji w obrocie oraz całkowitej liczby akcji posiadanych przez insiderów. Liczba ta waha się od 0 do 100, przy czym wyższe liczby wskazują na wyższy poziom akumulacji w porównaniu z innymi spółkami, a 50 to średnia.
Częstotliwość aktualizacji: codziennie
Ocena sentymentu kadry kierowniczej
Ocena sentymentu kadry kierowniczej pokazuje, że firmy są kupowane przez urzędników korporacyjnych.
Z definicji dyrektorzy korporacyjni to insiderzy korporacyjni, ale w przeciwieństwie do niektórych innych insiderów (10% akcjonariuszy i członków zarządu), dyrektorzy pracują dla firmy na co dzień i podczas handlu korzystają z własnych pieniędzy. (10% Akcjonariusze i członkowie zarządu często zarządzają funduszami zarządzających pieniędzmi innych osób). W związku z tym transakcje wykorzystujące informacje poufne dokonywane przez osoby z kadry kierowniczej mają znacznie większe znaczenie i powinny być odpowiednio traktowane.
Podobnie jak ocena sentymentu insiderów, ocena sentymentu kadry kierowniczej jest wynikiem zaawansowanego, wieloczynnikowego modelu ilościowego, który identyfikuje firmy o najwyższym poziomie akumulacji urzędników.
Częstotliwość aktualizacji: codziennie
Kluczowe wskaźniki insider
Ta karta pokazuje pozycję firmy według różnych wskaźników insider. Ranking według miary percentyla pokazuje, jak ta firma wypada na tle innych firm na rynkach amerykańskich. Wyższe rankingi wskazują na lepszą sytuację.
Na przykład ogólnie przyjmuje się, że kupowanie przez insiderów jest pozytywnym wskaźnikiem, zatem spółki z większą liczbą takich transakcji plasowałyby się wyżej niż spółki z mniejszą liczbą takich transakcji (lub nawet sprzedaży przez insiderów.
Liczba netto zakupów dokonanych przez insiderów (ranking)
N/A
Liczba netto zakupów dokonanych przez insiderów to łączna liczba insiderów kupujących pomniejszona o całkowitą liczbę insiderów sprzedających w ciągu ostatnich 90 dni. Tutaj pokazana jest miara percentyla (zakres od 0 do 100%).
Procent akcji kupowanych przez insiderów (ranking)
N/A
Procent akcji zakupionych przez insiderów to całkowita liczba akcji zakupionych przez insiderów pomniejszona o całkowitą liczbę akcji sprzedanych przez insiderów w ciągu ostatnich 90 dni, podzielona przez całkowitą liczbę akcji zakupionych przez insiderów i pomnożona przez 100.
Wykres handlu insider
Poniższy wykres przedstawia Targacept transakcji zrealizowanych przez insiderów. Insiderzy to członkowie kadry kierowniczej, dyrektorzy lub znaczący inwestorzy w spółce. Ogólnie rzecz biorąc, dokonywanie transakcji w ich firmach przez osoby posiadające dostęp do informacji poufnych w oparciu o istotne, niepubliczne informacje jest generalnie nielegalne. Nie oznacza to, że dokonywanie jakichkolwiek transakcji we własnych firmach jest nielegalne. Muszą jednak zgłaszać wszystkie transakcje do SEC za pośrednictwem formularza 4.
Lista insiderów i wskaźniki rentowności
Ta tabela przedstawia listę znanych insiderów i jest generowana automatycznie na podstawie zgłoszeń ujawnianych SEC. Oprócz nazwisk, najnowszego tytułu oraz oznaczenia dyrektora, członka kierownictwa lub 10% właściciela, podajemy najnowsze ujawnione pakiety akcji. Dodatkowo, jeśli to możliwe, udostępniamy historyczne wyniki handlowe danego insidera. Historyczne wyniki handlowe to średnia ważona wyników rzeczywistych transakcji zakupu na otwartym rynku dokonanych przez insiderów. Więcej informacji na temat sposobu obliczania tej wartości obejrzyj webinar na YouTube.
See our leaderboard of most profitable insider traders.
| Insider | Średni zysk (%) | Posiadane Akcje |
Podział korygujący |
|---|
Report errors via our new Insider Auditing Tool
Śledź historię zakupów insiderów — analiza zysków krótkoterminowych
W tej sekcji analizujemy rentowność każdego nieplanowanego zakupu od poufnych informacji na otwartym rynku dokonanego w TRGT / Targacept. Analiza ta pomaga zrozumieć, czy insider konsekwentnie generuje nietypowe zyski i czy warto ją śledzić. Analiza ta obejmuje okres jednego roku po każdej transakcji wyniki są teoretyczne .
Poniższa tabela przedstawia najnowsze zakupy na otwartym rynku, które nie były częścią planu handlu automatycznego.
Cena skorygowana to cena skorygowana o podział. Akcje skorygowane to akcje skorygowane o podział.
Śledź historię sprzedaży insider — analiza strat krótkoterminowych
W tej sekcji analizujemy możliwość uniknięcia krótkoterminowych strat w wyniku każdej nieplanowanej sprzedaży insidera na otwartym rynku dokonanej w TRGT / Targacept. Konsekwentny wzorzec unikania strat może sugerować, że przyszłe transakcje sprzedaży mogą przewidywać spadki cen. Analiza ta obejmuje okres jednego roku po każdej transakcji wyniki są teoretyczne .
Poniższa tabela przedstawia najnowsze sprzedaże na otwartym rynku, które nie były częścią planu handlu automatycznego.
Cena skorygowana to cena skorygowana o podział. Akcje skorygowane to akcje skorygowane o podział.
Historia transakcji
Kliknij ikonę linku, aby zobaczyć pełną historię transakcji. Transakcje zgłoszone w ramach automatycznego planu handlowego 10b5-1 będą oznaczone znakiem X w kolumnie oznaczonej 10b-5.
| Plik Data |
Data transakcji |
Formularz | Wtajemniczony | Serce | Nazwa papieru wartościowego | Kod | Bezpośredni | Cena wykonania |
Cena jednostki |
Zmieniono jednostki |
Zmieniona wartość (1 tys.) |
Pozostałe opcje |
Pozostałe akcje |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-05-27 | 2026-05-26 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,1001 | -4 000 | -24 | 700 000 | ||||
| 2026-05-27 | 2026-05-26 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 4 000 | 3 | 704 000 | ||||
| 2026-05-27 | 2026-05-22 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,0800 | -3 500 | -21 | 700 000 | ||||
| 2026-05-27 | 2026-05-22 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 3 500 | 3 | 703 500 | ||||
| 2026-05-22 | 2026-05-21 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,1500 | -12 820 | -79 | 700 000 | ||||
| 2026-05-22 | 2026-05-21 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 12 820 | 10 | 712 820 | ||||
| 2026-05-22 | 2026-05-20 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,1500 | -9 400 | -58 | 700 000 | ||||
| 2026-05-22 | 2026-05-20 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 9 400 | 7 | 709 400 | ||||
| 2026-05-20 | 2026-05-19 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,3700 | -9 120 | -58 | 700 000 | ||||
| 2026-05-20 | 2026-05-19 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 9 120 | 7 | 709 120 | ||||
| 2026-05-20 | 2026-05-18 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,6200 | -200 | -1 | 700 000 | ||||
| 2026-05-20 | 2026-05-18 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 200 | 0 | 700 200 | ||||
| 2026-05-18 | 2026-05-15 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,6500 | -13 100 | -87 | 700 000 | ||||
| 2026-05-18 | 2026-05-15 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 13 100 | 10 | 713 100 | ||||
| 2026-05-18 | 2026-05-14 | 4 | Ye Weiguo | GYRE | Common Stock | D | 6,9100 | -15 580 | -108 | 700 000 | ||||
| 2026-05-18 | 2026-05-14 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 15 580 | 12 | 715 580 | ||||
| 2026-05-07 | 2026-05-06 | 4 | Luo Ying By Spouse | GYRE | Common Stock | I | 8,0400 | -10 136 | -81 | 2 565 226 | ||||
| 2026-05-07 | 2026-05-05 | 4 | Luo Ying By Spouse | GYRE | Common Stock | I | 8,0100 | -179 | -1 | 2 575 362 | ||||
| 2026-05-07 | 3 | Luo Ying By Spouse | GYRE | Common Stock | I | 2 575 541 | ||||||||
| 2025-05-29 | 2025-05-28 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,0700 | -558 | -6 | 2 806 084 | ||||
| 2025-05-29 | 2025-05-27 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,2800 | -2 000 | -21 | 2 806 642 | ||||
| 2025-05-27 | 2025-05-23 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,2400 | -182 | -2 | 2 808 642 | ||||
| 2025-05-27 | 2025-05-22 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,9700 | -2 000 | -22 | 2 808 824 | ||||
| 2025-05-22 | 2025-05-21 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,8300 | -2 000 | -22 | 2 810 824 | ||||
| 2025-05-22 | 2025-05-20 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,2500 | -2 000 | -22 | 2 812 824 | ||||
| 2025-05-20 | 2025-05-19 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,1100 | -2 000 | -22 | 2 814 824 | ||||
| 2025-05-20 | 2025-05-16 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,3100 | -2 000 | -23 | 2 816 824 | ||||
| 2025-05-16 | 2025-05-15 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,6800 | -2 000 | -21 | 2 818 824 | ||||
| 2025-05-16 | 2025-05-14 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,3000 | -20 | -0 | 2 820 824 | ||||
| 2025-05-14 | 2025-04-01 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 50 000 | 38 | 700 000 | ||||
| 2025-05-14 | 2025-05-13 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,3700 | -2 000 | -23 | 2 820 844 | ||||
| 2025-05-14 | 2025-05-12 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,5600 | -2 000 | -21 | 2 822 844 | ||||
| 2025-04-25 | 2025-03-27 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 150 000 | 112 | 650 000 | ||||
| 2025-04-25 | 2025-03-26 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 200 000 | 150 | 500 000 | ||||
| 2025-04-25 | 2025-03-24 | 4 | Ye Weiguo | GYRE | Common Stock | D | 0,7500 | 300 000 | 225 | 300 000 | ||||
| 2025-04-18 | 2025-04-16 | 4 | Eastling Thomas Wilson | GYRE | Common Stock | D | 6,9300 | 15 000 | 104 | 15 000 | ||||
| 2025-03-25 | 2025-03-21 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,0000 | -174 | -2 | 2 824 844 | ||||
| 2025-03-21 | 2025-03-20 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,0900 | -2 000 | -20 | 2 825 018 | ||||
| 2025-03-21 | 2025-03-19 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,1300 | -2 000 | -20 | 2 827 018 | ||||
| 2025-03-19 | 2025-03-18 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,2400 | -242 | -2 | 2 829 018 | ||||
| 2025-03-19 | 2025-03-17 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,0900 | -2 000 | -24 | 2 829 260 | ||||
| 2025-03-17 | 2025-03-14 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,3100 | -2 000 | -25 | 2 831 260 | ||||
| 2025-03-17 | 2025-03-13 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,8000 | -2 000 | -24 | 2 833 260 | ||||
| 2025-03-13 | 2025-03-12 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,7400 | -2 000 | -23 | 2 835 260 | ||||
| 2025-03-13 | 2025-03-11 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,4000 | -2 000 | -23 | 2 837 260 | ||||
| 2025-03-11 | 2025-03-10 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,1400 | -2 000 | -20 | 2 839 260 | ||||
| 2025-03-11 | 2025-03-07 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,1300 | -1 906 | -19 | 2 841 260 | ||||
| 2025-03-11 | 2025-03-07 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,1400 | -41 | -0 | 2 843 166 | ||||
| 2025-03-11 | 2025-03-07 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 13,0300 | -53 | -1 | 2 843 207 | ||||
| 2025-03-07 | 2025-03-06 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,8000 | -2 000 | -22 | 2 843 260 | ||||
| 2025-03-07 | 2025-03-05 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,9800 | -2 000 | -22 | 2 845 260 | ||||
| 2025-03-05 | 2025-03-04 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,8600 | -2 000 | -22 | 2 847 260 | ||||
| 2025-03-05 | 2025-03-03 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,2300 | -2 000 | -22 | 2 849 260 | ||||
| 2025-03-03 | 2025-02-28 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,4100 | -2 000 | -23 | 2 851 260 | ||||
| 2025-03-03 | 2025-02-27 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,3300 | -2 000 | -23 | 2 853 260 | ||||
| 2025-02-27 | 2025-02-26 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,6300 | -2 000 | -23 | 2 855 260 | ||||
| 2025-02-27 | 2025-02-25 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,3700 | -2 000 | -23 | 2 857 260 | ||||
| 2025-02-25 | 2025-02-24 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,5200 | -187 | -2 | 2 859 260 | ||||
| 2025-02-25 | 2025-02-24 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,6000 | -1 813 | -19 | 2 859 447 | ||||
| 2025-02-25 | 2025-02-21 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,6000 | -182 | -2 | 2 861 260 | ||||
| 2025-02-25 | 2025-02-21 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,8400 | -1 818 | -22 | 2 861 442 | ||||
| 2025-02-21 | 2025-02-20 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,4000 | -2 000 | -25 | 2 863 260 | ||||
| 2025-02-21 | 2025-02-19 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,2900 | -2 000 | -25 | 2 865 260 | ||||
| 2025-02-19 | 2025-02-18 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,4900 | -2 000 | -25 | 2 867 260 | ||||
| 2025-02-19 | 2025-02-14 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,9400 | -2 000 | -24 | 2 869 260 | ||||
| 2025-02-14 | 2025-02-13 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,6900 | -2 000 | -23 | 2 871 260 | ||||
| 2025-02-14 | 2025-02-12 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,4900 | -2 000 | -23 | 2 873 260 | ||||
| 2025-02-12 | 2025-02-11 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,5200 | -1 878 | -22 | 2 875 260 | ||||
| 2025-02-12 | 2025-02-10 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,9000 | -2 000 | -24 | 2 877 138 | ||||
| 2025-02-11 | 2025-02-07 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,1600 | -2 000 | -24 | 2 879 158 | ||||
| 2025-02-11 | 2025-02-06 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,8500 | -2 000 | -26 | 2 881 138 | ||||
| 2025-02-06 | 2025-02-05 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,8400 | -20 | -0 | 2 883 138 | ||||
| 2025-02-06 | 2025-02-05 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,3900 | -1 980 | -25 | 2 883 158 | ||||
| 2025-02-06 | 2025-02-04 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,6200 | -2 000 | -23 | 2 885 138 | ||||
| 2025-02-04 | 2025-02-03 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,4700 | -2 000 | -23 | 2 887 138 | ||||
| 2025-02-04 | 2025-01-31 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,5100 | -2 000 | -23 | 2 889 138 | ||||
| 2025-01-31 | 2025-01-30 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,3700 | -2 000 | -23 | 2 891 138 | ||||
| 2025-01-31 | 2025-01-29 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,4300 | -2 000 | -23 | 2 893 138 | ||||
| 2025-01-29 | 2025-01-28 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,5100 | -2 000 | -23 | 2 895 138 | ||||
| 2025-01-29 | 2025-01-27 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,1800 | -2 000 | -22 | 2 897 138 | ||||
| 2025-01-27 | 2025-01-24 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,8900 | -2 000 | -22 | 2 899 138 | ||||
| 2025-01-27 | 2025-01-23 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,4900 | -2 000 | -21 | 2 901 138 | ||||
| 2025-01-24 | 2025-01-22 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,6300 | -2 000 | -21 | 2 903 138 | ||||
| 2025-01-24 | 2025-01-21 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,8500 | -2 000 | -22 | 2 905 138 | ||||
| 2025-01-21 | 2025-01-17 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,7200 | -2 000 | -21 | 2 907 138 | ||||
| 2025-01-21 | 2025-01-16 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,7100 | -2 000 | -21 | 2 909 138 | ||||
| 2025-01-16 | 2025-01-15 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,8500 | -2 000 | -22 | 2 911 138 | ||||
| 2025-01-16 | 2025-01-14 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,3900 | -2 000 | -21 | 2 913 138 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,1000 | -56 | -1 | 2 915 138 | ||||
| 2025-01-14 | 2025-01-10 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,0200 | -1 057 | -11 | 2 915 194 | ||||
| 2025-01-10 | 2025-01-03 | 4/A | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,8500 | -833 | -10 | 2 918 467 | ||||
| 2025-01-08 | 2025-01-07 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,0200 | -1 275 | -13 | 2 916 251 | ||||
| 2025-01-08 | 2025-01-06 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,1600 | -941 | -10 | 2 917 526 | ||||
| 2025-01-06 | 2025-01-03 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,0300 | -1 167 | -13 | 2 919 300 | ||||
| 2025-01-06 | 2025-01-02 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,4000 | -2 000 | -25 | 2 920 467 | ||||
| 2025-01-06 | 2024-01-03 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,8500 | -833 | -10 | 2 918 467 | ||||
| 2025-01-02 | 2024-12-31 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,3000 | -2 000 | -25 | 2 922 467 | ||||
| 2025-01-02 | 2024-12-30 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,5000 | -2 000 | -25 | 2 924 467 | ||||
| 2024-12-30 | 2024-12-27 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,5800 | -2 000 | -25 | 2 926 467 | ||||
| 2024-12-30 | 2024-12-26 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 13,0500 | -356 | -5 | 2 928 467 | ||||
| 2024-12-30 | 2024-12-26 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,6200 | -1 644 | -21 | 2 928 823 | ||||
| 2024-12-26 | 2024-12-24 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,9300 | -2 000 | -24 | 2 930 467 | ||||
| 2024-12-26 | 2024-12-23 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,4400 | -296 | -4 | 2 932 467 | ||||
| 2024-12-26 | 2024-12-23 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,2400 | -1 704 | -21 | 2 932 763 | ||||
| 2024-12-23 | 2024-12-20 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,9000 | -2 000 | -22 | 2 934 467 | ||||
| 2024-12-23 | 2024-12-19 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,8200 | -2 000 | -22 | 2 936 467 | ||||
| 2024-12-19 | 2024-12-18 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 12,1100 | -429 | -5 | 2 938 467 | ||||
| 2024-12-19 | 2024-12-18 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,1700 | -1 571 | -18 | 2 938 896 | ||||
| 2024-12-19 | 2024-12-17 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 11,2300 | -788 | -9 | 2 940 467 | ||||
| 2024-12-19 | 2024-12-17 | 4 | Ma Songjiang By Spouse | GYRE | Common Stock | I | 10,9400 | -1 212 | -13 | 2 941 255 | ||||
| 2024-07-01 | 2024-06-28 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 12,0040 | -3 452 | -41 | 1 636 | ||||
| 2024-07-01 | 2024-06-28 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 6,9300 | 3 452 | 24 | 5 088 | ||||
| 2024-05-02 | 2024-05-01 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 15,6300 | -100 | -2 | 1 636 | ||||
| 2024-05-02 | 2024-05-01 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 14,9000 | -5 000 | -74 | 1 736 | ||||
| 2024-05-02 | 2024-05-01 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 13,8600 | -14 900 | -207 | 6 736 | ||||
| 2024-05-02 | 2024-05-01 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 6,9300 | 20 000 | 139 | 21 636 | ||||
| 2024-04-03 | 2024-04-01 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 16,1500 | -20 000 | -323 | 1 636 | ||||
| 2024-04-03 | 2024-04-01 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 6,9300 | 20 000 | 139 | 21 636 | ||||
| 2024-03-19 | 2024-03-15 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 17,2600 | -20 000 | -345 | 1 636 | ||||
| 2024-03-19 | 2024-03-15 | 4 | USMAN NASSIM | GYRE | Common Stock | D | 6,9300 | 20 000 | 139 | 21 636 | ||||
| 2023-11-22 | 3/A | Ma Songjiang By Spouse | GYRE | Common Stock | I | 2 942 467 | ||||||||
| 2023-11-22 | 2023-10-30 | 4 | GNI Group Ltd. See Remarks | GYRE | Common Stock | I | 63 588 119 | 64 005 887 | ||||||
| 2023-11-22 | 2023-10-30 | 4 | Luo Ying By Spouse | GYRE | Common Stock | I | 2 840 376 | 2 840 376 | ||||||
| 2023-10-27 | 3 | GNI Group Ltd. | CBIO | Common Stock | I | 6 266 521 | ||||||||
| 2023-10-27 | 2023-10-27 | 4 | GNI Hong Kong Ltd | CBIO | Common Stock | D | -5 371 304 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | LAWLOR AUGUSTINE By The Lawlor Family Trust UAD 4-17-00 | CBIO | Series Y Preferred Stock | I | -24 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | LAWLOR AUGUSTINE | CBIO | Series Y Preferred Stock | D | -25 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | GNI Group Ltd. | CBIO | Series Y Preferred Stock | D | -5 371 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | GNI Group Ltd. | CBIO | Series Y Preferred Stock | D | -895 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | USMAN NASSIM By Nassim Usman IRA | CBIO | Series Y Preferred Stock | I | -1 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | USMAN NASSIM By The Usman Family Trust | CBIO | Series Y Preferred Stock | I | -8 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | USMAN NASSIM | CBIO | Series Y Preferred Stock | D | -25 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | Hunt Andrea | CBIO | Series Y Preferred Stock | D | -28 | 0 | ||||||
| 2023-09-01 | 2023-08-31 | 4 | Miller Seline E. | CBIO | Series Y Preferred Stock | D | -6 | 0 | ||||||
| 2023-01-05 | 3 | GNI Hong Kong Ltd | CBIO | Common Stock | D | 895 217 | ||||||||
| 2023-01-05 | 3 | GNI Hong Kong Ltd | CBIO | Common Stock | D | 5 371 304 | ||||||||
| 2022-08-10 | 2022-08-09 | 4 | Miller Seline E. | CBIO | Common Stock | D | 0,4700 | 3 250 | 2 | 6 500 | ||||
| 2022-08-10 | 2022-08-09 | 4 | Blouse Grant E. | CBIO | Common Stock | D | 0,4700 | 3 250 | 2 | 9 417 | ||||
| 2022-08-10 | 2022-08-09 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 0,4700 | 3 250 | 2 | 24 541 | ||||
| 2022-02-23 | 2022-02-11 | 4 | Miller Seline E. | CBIO | Stock Option (Right to Buy) | D | 0,52 | 107 500 | 107 500 | |||||
| 2022-02-23 | 2022-02-11 | 4 | Blouse Grant E. | CBIO | Stock Option (Right to Buy) | D | 0,52 | 200 000 | 200 000 | |||||
| 2022-02-16 | 2022-02-09 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 0,4600 | 3 250 | 1 | 21 291 | ||||
| 2022-02-16 | 2022-02-09 | 4 | Miller Seline E. | CBIO | Common Stock | D | 0,4600 | 3 250 | 1 | 3 250 | ||||
| 2022-02-16 | 2022-02-09 | 4 | Blouse Grant E. | CBIO | Common Stock | D | 0,4600 | 3 250 | 1 | 6 167 | ||||
| 2022-01-07 | 2022-01-07 | 4 | Williams Eddie | CBIO | Common Stock | D | 12 308 | 34 804 | ||||||
| 2022-01-07 | 2022-01-07 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 12 855 | 31 790 | ||||||
| 2022-01-07 | 2022-01-07 | 4 | Hunt Andrea | CBIO | Common Stock | D | 7 521 | 28 228 | ||||||
| 2021-10-05 | 2021-10-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 2 980 | 22 496 | ||||||
| 2021-10-05 | 2021-10-01 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 2 858 | 18 935 | ||||||
| 2021-10-05 | 2021-10-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 5 839 | 24 573 | ||||||
| 2021-10-05 | 2021-10-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 3 588 | 29 801 | ||||||
| 2021-10-05 | 2021-10-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 1 824 | 20 707 | ||||||
| 2021-09-13 | 2021-09-09 | 4 | JEW JEANNE Y | CBIO | Stock Option (Right to Buy) | D | 4,38 | 28 000 | 28 000 | |||||
| 2021-08-11 | 2021-08-09 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 3,6200 | 867 | 3 | 18 041 | ||||
| 2021-08-11 | 2021-08-09 | 4 | Levy Howard | CBIO | Common Stock | D | 3,6200 | 639 | 2 | 639 | ||||
| 2021-08-11 | 2021-08-09 | 4 | Blouse Grant E. | CBIO | Common Stock | D | 3,6200 | 1 163 | 4 | 2 917 | ||||
| 2021-07-15 | 3 | Blouse Grant E. | CBIO | Common Stock | D | 1 754 | ||||||||
| 2021-07-02 | 2021-06-09 | 4 | TETLOW SHARON | CBIO | Stock Option (Right to Buy) | D | 4,55 | 14 000 | 14 000 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 414 | 19 516 | ||||||
| 2021-07-02 | 2021-06-09 | 4 | Williams Eddie | CBIO | Stock Option (Right to Buy) | D | 4,55 | 14 000 | 14 000 | |||||
| 2021-07-02 | 2021-07-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 5 542 | 18 734 | ||||||
| 2021-07-02 | 2021-06-09 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 4,55 | 14 000 | 14 000 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 2 713 | 16 077 | ||||||
| 2021-07-02 | 2021-06-09 | 4 | Ling Geoffrey M.D. | CBIO | Stock Option (Right to Buy) | D | 4,55 | 14 000 | 14 000 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 2 886 | 18 883 | ||||||
| 2021-07-02 | 2021-06-09 | 4 | Hunt Andrea | CBIO | Stock Option (Right to Buy) | D | 4,55 | 14 000 | 14 000 | |||||
| 2021-07-02 | 2021-07-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 3 406 | 26 213 | ||||||
| 2021-07-02 | 2021-06-09 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 4,55 | 14 000 | 14 000 | |||||
| 2021-04-26 | 2021-02-08 | 4/A | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 5,89 | 140 000 | 140 000 | |||||
| 2021-04-26 | 2021-02-08 | 4/A | Musil Clinton | CBIO | Stock Option (Right to Buy) | D | 5,89 | 54 000 | 54 000 | |||||
| 2021-04-26 | 2021-02-08 | 4/A | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 5,89 | 25 000 | 25 000 | |||||
| 2021-04-07 | 2021-04-05 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,63 | -5 000 | 259 783 | |||||
| 2021-04-07 | 2021-04-05 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 4,6300 | 5 000 | 23 | 17 174 | ||||
| 2021-04-05 | 2021-04-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 215 | 18 102 | ||||||
| 2021-04-05 | 2021-04-01 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 2 331 | 13 364 | ||||||
| 2021-04-05 | 2021-04-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 4 761 | 13 192 | ||||||
| 2021-04-05 | 2021-04-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 2 926 | 22 807 | ||||||
| 2021-04-05 | 2021-04-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 2 480 | 15 997 | ||||||
| 2021-02-22 | 2021-02-09 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 4,8100 | 582 | 3 | 12 174 | ||||
| 2021-02-22 | 2021-02-09 | 4 | Levy Howard By Howard and Gillian Levy Revocable Trust dated November 21, 1994 | CBIO | Common Stock | I | 4,8100 | 1 670 | 8 | 23 390 | ||||
| 2021-02-10 | 2021-02-08 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 5,89 | 140 000 | 140 000 | |||||
| 2021-02-10 | 2021-02-08 | 4 | Musil Clinton | CBIO | Stock Option (Right to Buy) | D | 5,89 | 54 000 | 54 000 | |||||
| 2021-02-10 | 2021-02-08 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 5,89 | 25 000 | 25 000 | |||||
| 2021-01-06 | 2021-01-05 | 4 | Williams Eddie | CBIO | Common Stock | D | 940 | 16 887 | ||||||
| 2021-01-06 | 2021-01-05 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 1 782 | 11 033 | ||||||
| 2021-01-06 | 2021-01-05 | 4 | Hunt Andrea | CBIO | Common Stock | D | 1 881 | 13 517 | ||||||
| 2021-01-06 | 2021-01-05 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 3 417 | 8 431 | ||||||
| 2021-01-06 | 2021-01-05 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 2 129 | 19 881 | ||||||
| 2020-10-02 | 2020-10-01 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 2 616 | 9 251 | ||||||
| 2020-10-02 | 2020-10-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 380 | 15 947 | ||||||
| 2020-10-02 | 2020-10-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 5 014 | 5 014 | ||||||
| 2020-10-02 | 2020-10-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 3 125 | 17 752 | ||||||
| 2020-10-02 | 2020-10-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 2 761 | 11 636 | ||||||
| 2020-08-12 | 2020-08-10 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 4,8100 | 582 | 3 | 11 592 | ||||
| 2020-08-12 | 2020-08-10 | 4 | Levy Howard | CBIO | Common Stock | D | 4,8100 | 1 768 | 9 | 4 268 | ||||
| 2020-07-02 | 2020-07-01 | 4 | Musil Clinton | CBIO | Stock Option (Right to Buy) | D | 5,88 | 140 000 | 140 000 | |||||
| 2020-07-02 | 2020-07-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 2 076 | 8 875 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 3 673 | 24 215 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 1 703 | 6 635 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | TETLOW SHARON | CBIO | Common Stock | D | 1 703 | 3 635 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 011 | 14 567 | ||||||
| 2020-07-02 | 2020-07-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 2 129 | 14 627 | ||||||
| 2020-06-12 | 2020-06-11 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 7,18 | 5 000 | 5 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | Hunt Andrea | CBIO | Stock Option (Right to Buy) | D | 7,18 | 5 000 | 5 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 7,18 | 5 000 | 5 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | Ling Geoffrey M.D. | CBIO | Stock Option (Right to Buy) | D | 7,18 | 5 000 | 5 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | TETLOW SHARON | CBIO | Stock Option (Right to Buy) | D | 7,18 | 5 000 | 5 000 | |||||
| 2020-06-12 | 2020-06-11 | 4 | Williams Eddie | CBIO | Stock Option (Right to Buy) | D | 7,18 | 5 000 | 5 000 | |||||
| 2020-04-03 | 2020-04-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 1 673 | 6 799 | ||||||
| 2020-04-03 | 2020-04-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 4 934 | 20 542 | ||||||
| 2020-04-03 | 2020-04-01 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 1 932 | 4 932 | ||||||
| 2020-04-03 | 2020-04-01 | 4 | TETLOW SHARON | CBIO | Common Stock | D | 1 932 | 1 932 | ||||||
| 2020-04-03 | 2020-04-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 2 717 | 13 556 | ||||||
| 2020-04-03 | 2020-04-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 2 860 | 12 498 | ||||||
| 2020-03-17 | 2020-03-16 | 4 | Levy Howard | CBIO | Common Stock | D | 4,0526 | 2 500 | 10 | 2 500 | ||||
| 2020-03-13 | 2020-03-13 | 4 | Cai Veronica | CBIO | Common Stock | D | 4,1100 | 2 000 | 8 | 7 353 | ||||
| 2020-03-13 | 2020-03-13 | 4 | Richard John P | CBIO | Common Stock | D | 3,9800 | 2 500 | 10 | 3 716 | ||||
| 2020-03-13 | 2020-03-13 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 3,9118 | 4 000 | 16 | 11 010 | ||||
| 2020-03-04 | 2020-03-04 | 4 | Williams Eddie | CBIO | Common Stock | D | 5,7800 | 2 000 | 12 | 10 839 | ||||
| 2020-02-27 | 2020-02-25 | 4 | Ling Geoffrey M.D. | CBIO | Common Stock | D | 6,2305 | 3 000 | 19 | 3 000 | ||||
| 2020-02-25 | 2020-02-25 | 4 | LAWLOR AUGUSTINE By HealthCare Ventures VIII, L.P. | CBIO | Common Stock | I | 6,1023 | -69 401 | -424 | 0 | ||||
| 2020-02-12 | 2020-02-10 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 6,2300 | 430 | 3 | 7 010 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Cai Veronica | CBIO | Common Stock | D | 6,2300 | 1 678 | 10 | 5 353 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Levy Howard | CBIO | Common Stock | D | 6,2300 | 1 358 | 8 | 1 358 | ||||
| 2020-01-27 | 3 | Cai Veronica | CBIO | Common Stock | D | 5 350 | ||||||||
| 2020-01-27 | 3 | Cai Veronica | CBIO | Common Stock | D | 5 350 | ||||||||
| 2020-01-27 | 3 | Cai Veronica | CBIO | Common Stock | D | 5 350 | ||||||||
| 2020-01-27 | 2019-09-16 | 4 | Cai Veronica | CBIO | Stock Option (Right to Buy) | D | 6,22 | 3 000 | 3 000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | Cai Veronica | CBIO | Stock Option (Right to Buy) | D | 6,85 | 12 000 | 12 000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 6,85 | 115 000 | 115 000 | |||||
| 2020-01-27 | 2020-01-23 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 6,85 | 45 000 | 45 000 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Ling Geoffrey M.D. | CBIO | Stock Option (Right to Buy) | D | 7,29 | 10 000 | 10 000 | |||||
| 2020-01-17 | 2020-01-15 | 4 | TETLOW SHARON | CBIO | Stock Option (Right to Buy) | D | 7,29 | 10 000 | 10 000 | |||||
| 2020-01-02 | 2020-01-02 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 1 835 | 9 638 | ||||||
| 2020-01-02 | 2020-01-02 | 4 | Hunt Andrea | CBIO | Common Stock | D | 1 073 | 5 126 | ||||||
| 2020-01-02 | 2020-01-02 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 3 166 | 15 608 | ||||||
| 2020-01-02 | 2020-01-02 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 743 | 8 839 | ||||||
| 2019-10-02 | 2019-10-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 1 489 | 4 053 | ||||||
| 2019-10-02 | 2019-10-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 2 418 | 7 096 | ||||||
| 2019-10-02 | 2019-10-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 2 545 | 7 803 | ||||||
| 2019-10-02 | 2019-10-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 4 391 | 12 442 | ||||||
| 2019-08-12 | 2019-08-12 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 6,5100 | 413 | 3 | 6 580 | ||||
| 2019-08-12 | 2019-08-12 | 4 | Payne Fletcher | CBIO | Common Stock | D | 6,5100 | 1 180 | 8 | 3 744 | ||||
| 2019-07-02 | 2019-07-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 1 036 | 2 564 | ||||||
| 2019-07-02 | 2019-07-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 2 905 | 8 051 | ||||||
| 2019-07-02 | 2019-07-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 642 | 4 678 | ||||||
| 2019-07-02 | 2019-07-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 1 810 | 5 258 | ||||||
| 2019-06-17 | 2019-06-13 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 7,46 | 5 000 | 5 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | Hunt Andrea | CBIO | Stock Option (Right to Buy) | D | 7,46 | 5 000 | 5 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | Richard John P | CBIO | Stock Option (Right to Buy) | D | 7,46 | 5 000 | 5 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | Williams Eddie | CBIO | Stock Option (Right to Buy) | D | 7,46 | 5 000 | 5 000 | |||||
| 2019-06-17 | 2019-06-13 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 7,46 | 5 000 | 5 000 | |||||
| 2019-05-28 | 2019-05-24 | 4 | Richard John P | CBIO | Common Stock | D | 8,0300 | 1 000 | 8 | 1 216 | ||||
| 2019-05-22 | 2019-05-21 | 4 | USMAN NASSIM By The Usman Family Trust | CBIO | Common Stock | I | 4 400 | 8 456 | ||||||
| 2019-05-22 | 2019-05-21 | 4 | USMAN NASSIM | CBIO | Common Stock | D | -4 400 | 6 167 | ||||||
| 2019-05-22 | 2019-05-21 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 4,6300 | 4 400 | 20 | 10 567 | ||||
| 2019-05-22 | 2019-05-20 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,63 | -4 400 | 264 783 | |||||
| 2019-05-22 | 2019-05-21 | 4 | Levy Howard Howard and Gillian Levy Revocable Trust dated November 21, 1994 | CBIO | Common Stock | I | -16 094 | 16 094 | ||||||
| 2019-05-22 | 2019-05-21 | 4 | Levy Howard | CBIO | Common Stock | D | 4,6300 | 4 400 | 20 | 16 094 | ||||
| 2019-05-22 | 2019-05-20 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 4,63 | -4 400 | 81 218 | |||||
| 2019-04-02 | 2019-04-01 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 1 504 | 3 448 | ||||||
| 2019-04-02 | 2019-04-01 | 4 | Hunt Andrea | CBIO | Common Stock | D | 717 | 1 528 | ||||||
| 2019-04-02 | 2019-04-01 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 2 414 | 5 146 | ||||||
| 2019-04-02 | 2019-04-01 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 364 | 3 036 | ||||||
| 2019-02-13 | 2019-02-11 | 4 | Payne Fletcher | CBIO | Common Stock | D | 7,0400 | 1 002 | 7 | 3 731 | ||||
| 2019-02-13 | 2019-02-11 | 4 | Levy Howard | CBIO | Common Stock | D | 7,0400 | 2 485 | 17 | 11 867 | ||||
| 2019-02-13 | 2019-02-11 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 7,0400 | 350 | 2 | 6 167 | ||||
| 2019-02-04 | 2019-01-31 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,63 | -5 729 | 269 271 | |||||
| 2019-02-04 | 2019-01-31 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 4,6300 | 5 729 | 27 | 11 041 | ||||
| 2019-02-04 | 2019-02-04 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 4,63 | -1 503 | 73 497 | |||||
| 2019-02-04 | 2019-02-04 | 4 | Payne Fletcher | CBIO | Common Stock | D | 4,6300 | 1 503 | 7 | 3 230 | ||||
| 2019-02-04 | 2019-01-31 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 4,63 | -1 500 | 93 500 | |||||
| 2019-02-04 | 2019-01-31 | 4 | Levy Howard | CBIO | Common Stock | D | 4,6300 | 1 500 | 7 | 9 382 | ||||
| 2019-01-28 | 2019-01-24 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 7,97 | 35 000 | 35 000 | |||||
| 2019-01-28 | 2019-01-24 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 7,97 | 38 000 | 38 000 | |||||
| 2019-01-28 | 2019-01-24 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 7,97 | 80 000 | 80 000 | |||||
| 2019-01-03 | 2018-12-31 | 4 | DESOUZA ERROL B | CBIO | Common Stock | D | 1 703 | 1 944 | ||||||
| 2019-01-03 | 2018-12-31 | 4 | Hunt Andrea | CBIO | Common Stock | D | 811 | 811 | ||||||
| 2019-01-03 | 2018-12-31 | 4 | LAWLOR AUGUSTINE | CBIO | Common Stock | D | 2 732 | 2 732 | ||||||
| 2019-01-03 | 2018-12-31 | 4 | Williams Eddie | CBIO | Common Stock | D | 1 544 | 1 672 | ||||||
| 2018-11-27 | 2018-11-26 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 4,63 | -149 | 87 118 | |||||
| 2018-11-27 | 2018-11-26 | 4 | Levy Howard | CBIO | Common Stock | D | 4,6300 | 149 | 1 | 7 709 | ||||
| 2018-11-16 | 2018-11-16 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 4,63 | -173 | 87 267 | |||||
| 2018-11-16 | 2018-11-16 | 4 | Levy Howard | CBIO | Common Stock | D | 11,0000 | -173 | -2 | 7 560 | ||||
| 2018-11-16 | 2018-11-16 | 4 | Levy Howard | CBIO | Common Stock | D | 4,6300 | 173 | 1 | 7 733 | ||||
| 2018-09-06 | 2018-09-06 | 4 | HILL STEPHEN A | CBIO | Common Stock | D | 10,0700 | -190 | -2 | 1 190 | ||||
| 2018-08-01 | 2018-07-30 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 9,68 | 35 000 | 35 000 | |||||
| 2018-08-01 | 2018-07-30 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 9,68 | 25 000 | 25 000 | |||||
| 2018-08-01 | 2018-07-30 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 9,68 | 75 000 | 75 000 | |||||
| 2018-07-27 | 3 | JFL Capital Management, LLC | CBIO | Catalyst Biosciences Inc common | D | 827 246 | ||||||||
| 2018-07-27 | 3 | JFL Capital Management, LLC Managed account | CBIO | Catalyst Biosciences Inc common | I | 1 022 671 | ||||||||
| 2018-07-27 | 3 | JFL Capital Management, LLC | CBIO | Catalyst Biosciences Inc common | D | 827 246 | ||||||||
| 2018-07-27 | 3 | JFL Capital Management, LLC Managed account | CBIO | Catalyst Biosciences Inc common | I | 1 022 671 | ||||||||
| 2018-07-27 | 3 | JFL Capital Management, LLC | CBIO | Catalyst Biosciences Inc common | D | 827 246 | ||||||||
| 2018-07-27 | 3 | JFL Capital Management, LLC Managed account | CBIO | Catalyst Biosciences Inc common | I | 1 022 671 | ||||||||
| 2018-06-15 | 2018-06-13 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 24,94 | 5 000 | 5 000 | |||||
| 2018-06-15 | 2018-06-13 | 4 | HILL STEPHEN A | CBIO | Stock Option (Right to Buy) | D | 24,94 | 5 000 | 5 000 | |||||
| 2018-06-15 | 2018-06-13 | 4 | Hunt Andrea | CBIO | Stock Option (Right to Buy) | D | 24,94 | 5 000 | 5 000 | |||||
| 2018-06-15 | 2018-06-13 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 24,94 | 5 000 | 5 000 | |||||
| 2018-06-15 | 2018-06-13 | 4 | Richard John P | CBIO | Stock Option (Right to Buy) | D | 24,94 | 5 000 | 5 000 | |||||
| 2018-06-15 | 2018-06-13 | 4 | Williams Eddie | CBIO | Stock Option (Right to Buy) | D | 24,94 | 5 000 | 5 000 | |||||
| 2018-05-04 | 2018-05-03 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 4,63 | -7 560 | 87 440 | |||||
| 2018-05-04 | 2018-05-03 | 4 | Levy Howard | CBIO | Common Stock | D | 4,6300 | 7 560 | 35 | 7 560 | ||||
| 2018-04-11 | 2018-04-09 | 4 | USMAN NASSIM By The Usman Family Trust | CBIO | Common Stock | I | 88 | 4 144 | ||||||
| 2018-04-11 | 2018-04-09 | 4 | USMAN NASSIM | CBIO | Common Stock | D | -88 | 0 | ||||||
| 2018-04-06 | 2018-04-04 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,63 | -88 | 274 912 | |||||
| 2018-04-06 | 2018-04-04 | 4 | USMAN NASSIM | CBIO | Common Stock | D | 4,6300 | 88 | 0 | 88 | ||||
| 2018-03-28 | 2018-03-26 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 4,63 | -59 | 74 941 | |||||
| 2018-03-28 | 2018-03-26 | 4 | Payne Fletcher | CBIO | Common Stock | D | 4,6300 | 59 | 0 | 59 | ||||
| 2018-03-21 | 2018-03-08 | 4/A | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 29,0300 | -2 233 | -65 | 305 965 | ||||
| 2018-03-21 | 2018-03-08 | 4/A | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common Stock | I | 29,0300 | -5 890 | -171 | 807 257 | ||||
| 2018-03-21 | 2018-03-08 | 4/A | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 30,0000 | -328 | -10 | 308 198 | ||||
| 2018-03-21 | 2018-03-08 | 4/A | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common Stock | I | 30,0000 | -866 | -26 | 813 147 | ||||
| 2018-03-21 | 2018-03-07 | 4/A | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 30,0000 | -2 748 | -82 | 308 526 | ||||
| 2018-03-21 | 2018-03-07 | 4/A | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common Stock | I | 30,0000 | -7 252 | -218 | 814 013 | ||||
| 2018-03-21 | 2018-03-06 | 4/A | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 31,1800 | -10 802 | -337 | 311 274 | ||||
| 2018-03-21 | 2018-03-06 | 4/A | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common Stock | I | 31,1800 | -28 498 | -889 | 821 265 | ||||
| 2018-03-21 | 2018-03-06 | 4/A | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 29,9400 | -3 617 | -108 | 322 076 | ||||
| 2018-03-21 | 2018-03-06 | 4/A | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common Stock | I | 29,9400 | -9 544 | -286 | 849 763 | ||||
| 2018-03-08 | 2018-03-08 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 29,0300 | -8 123 | -236 | 1 113 222 | ||||
| 2018-03-08 | 2018-03-08 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 30,0000 | -1 194 | -36 | 1 121 345 | ||||
| 2018-03-08 | 2018-03-07 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 30,0000 | -10 000 | -300 | 1 122 539 | ||||
| 2018-03-08 | 2018-03-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 31,1800 | -39 300 | -1 225 | 1 132 539 | ||||
| 2018-03-08 | 2018-03-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common Stock | I | 29,9400 | -13 161 | -394 | 1 171 839 | ||||
| 2018-02-22 | 2018-02-20 | 4 | DESOUZA ERROL B | CBIO | Redeemable Convertible Note | D | 137,85 | -4 679 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | DESOUZA ERROL B | CBIO | Redeemable Convertible Note | D | 137,85 | 0 | ||||||
| 2018-02-22 | 2018-02-20 | 4 | HILL STEPHEN A | CBIO | Redeemable Convertible Note | D | 137,85 | -21 600 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | HILL STEPHEN A | CBIO | Redeemable Convertible Note | D | 137,85 | 0 | ||||||
| 2018-02-22 | 2018-02-20 | 4 | Richard John P | CBIO | Redeemable Convertible Note | D | 137,85 | |||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common stock | I | 1 510 693 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common stock | I | 1 510 693 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common stock | I | 2 044 307 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common stock | I | 2 044 307 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common stock | I | 2 044 307 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common stock | I | 1 510 693 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common stock | I | 1 510 693 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common stock | I | 2 044 307 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common stock | I | 1 510 693 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common stock | I | 2 044 307 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Partners, L.P. | CBIO | Common stock | I | 2 044 307 | ||||||||
| 2018-02-15 | 3 | Flynn James E Through Deerfield Special Situations Fund, L.P. | CBIO | Common stock | I | 1 510 693 | ||||||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 4,40 | 10 000 | 10 000 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 4,40 | -10 000 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 28,20 | 500 | 500 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 28,20 | -500 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 66,00 | 450 | 450 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 66,00 | -450 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 66,00 | 550 | 550 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 66,00 | -550 | 0 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 157,20 | 197 | 197 | |||||
| 2018-01-18 | 2018-01-16 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 157,20 | -197 | 0 | |||||
| 2018-01-16 | 2018-01-12 | 4 | Levy Howard | CBIO | Stock Option(Right to Buy) | D | 15,13 | 33 000 | 33 000 | |||||
| 2018-01-16 | 2018-01-12 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 15,13 | 26 000 | 26 000 | |||||
| 2018-01-16 | 2018-01-12 | 4 | USMAN NASSIM | CBIO | Stock Option(Right to Buy) | D | 15,13 | 95 000 | 95 000 | |||||
| 2018-01-02 | 3 | Williams Eddie | CBIO | Common Stock | D | 256 | ||||||||
| 2018-01-02 | 3 | Williams Eddie | CBIO | Common Stock | D | 256 | ||||||||
| 2018-01-02 | 2018-01-02 | 4 | Williams Eddie | CBIO | Stock Option (Right to Buy) | D | 14,37 | 10 000 | 10 000 | |||||
| 2017-12-22 | 2017-12-20 | 4 | Richard John P | CBIO | Redeemable Convertible Note | D | 9,19 | |||||||
| 2017-10-26 | 2017-10-25 | 4 | Hunt Andrea | CBIO | Stock Option (Right to Buy) | D | 4,72 | 10 000 | 10 000 | |||||
| 2017-07-17 | 2017-07-13 | 4 | Richard John P | CBIO | Stock Option (Right to Buy) | D | 4,40 | 10 000 | 10 000 | |||||
| 2017-07-14 | 2017-07-13 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 4,40 | 10 000 | 10 000 | |||||
| 2017-07-14 | 2017-07-13 | 4 | HILL STEPHEN A | CBIO | Stock Option (Right to Buy) | D | 4,40 | 10 000 | 10 000 | |||||
| 2017-07-14 | 2017-07-13 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 4,40 | 10 000 | 10 000 | |||||
| 2017-07-14 | 2017-07-13 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 4,40 | 10 000 | 10 000 | |||||
| 2017-07-12 | 2017-07-11 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,63 | 275 000 | 275 000 | |||||
| 2017-07-12 | 2017-07-11 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 4,63 | 75 000 | 75 000 | |||||
| 2017-07-12 | 2017-07-11 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 4,63 | 95 000 | 95 000 | |||||
| 2016-06-13 | 2016-06-09 | 4/A | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 0 | 0 | ||||||
| 2016-06-13 | 2016-06-09 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 1,88 | 7 500 | 7 500 | |||||
| 2016-06-13 | 2016-06-09 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 1,88 | 7 500 | 7 500 | |||||
| 2016-06-13 | 2016-06-09 | 4 | HILL STEPHEN A | CBIO | Stock Option (Right to Buy) | D | 1,88 | 7 500 | 7 500 | |||||
| 2016-06-13 | 2016-06-09 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 1,88 | 7 500 | 7 500 | |||||
| 2016-06-13 | 2016-06-09 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 1,88 | 7 500 | 7 500 | |||||
| 2016-06-13 | 2016-06-09 | 4 | Richard John P | CBIO | Stock Option (Right to Buy) | D | 1,88 | 7 500 | 7 500 | |||||
| 2016-04-19 | 2016-04-18 | 4 | Levy Howard | CBIO | Stock Option (Right to Buy) | D | 1,52 | 100 000 | 100 000 | |||||
| 2015-12-18 | 2015-12-17 | 4 | USMAN NASSIM By Nassim Usman IRA | CBIO | Common Stock | I | 2,0000 | 4 000 | 8 | 78 375 | ||||
| 2015-12-18 | 2015-12-17 | 4 | Payne Fletcher By Charles and Nancy Payne 2000 Trust | CBIO | Common Stock | I | 2,0000 | 10 000 | 20 | 25 032 | ||||
| 2015-12-18 | 2015-12-17 | 4 | HILL STEPHEN A | CBIO | Common Stock | D | 2,0300 | 5 000 | 10 | 20 711 | ||||
| 2015-12-15 | 2015-10-22 | 4/A | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-12-15 | 2015-10-22 | 4/A | HILL STEPHEN A | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-12-15 | 2015-10-22 | 4/A | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-12-15 | 2015-10-22 | 4/A | Madison Edwin | CBIO | Stock Option (Right to Buy) | D | 4,40 | 58 572 | 58 572 | |||||
| 2015-12-15 | 2015-10-22 | 4/A | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 4,40 | 28 572 | 28 572 | |||||
| 2015-12-15 | 2015-10-22 | 4/A | Richard John P | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-12-15 | 2015-10-22 | 4/A | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-12-15 | 2015-10-22 | 4/A | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,40 | 153 572 | 153 572 | |||||
| 2015-10-26 | 2015-10-22 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-10-26 | 2015-10-22 | 4 | LAWLOR AUGUSTINE | CBIO | Stock Option (Right to Buy) | D | 4,40 | 8 250 | 8 250 | |||||
| 2015-10-26 | 2015-10-22 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-10-26 | 2015-10-22 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 4,40 | 8 250 | 8 250 | |||||
| 2015-10-26 | 2015-10-22 | 4 | HILL STEPHEN A | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-10-26 | 2015-10-22 | 4 | HILL STEPHEN A | CBIO | Stock Option (Right to Buy) | D | 4,40 | 8 250 | 8 250 | |||||
| 2015-10-26 | 2015-10-22 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-10-26 | 2015-10-22 | 4 | DESOUZA ERROL B | CBIO | Stock Option (Right to Buy) | D | 4,40 | 8 250 | 8 250 | |||||
| 2015-10-26 | 2015-10-22 | 4 | Richard John P | CBIO | Stock Option (Right to Buy) | D | 4,40 | 6 750 | 6 750 | |||||
| 2015-10-26 | 2015-10-22 | 4 | Richard John P | CBIO | Stock Option (Right to Buy) | D | 4,40 | 8 250 | 8 250 | |||||
| 2015-10-26 | 2015-10-22 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,40 | 153 572 | 153 572 | |||||
| 2015-10-26 | 2015-10-22 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 4,40 | 71 428 | 71 428 | |||||
| 2015-10-26 | 2015-10-22 | 4 | Madison Edwin | CBIO | Stock Option (Right to Buy) | D | 4,40 | 58 572 | 58 572 | |||||
| 2015-10-26 | 2015-10-22 | 4 | Madison Edwin | CBIO | Stock Option (Right to Buy) | D | 4,40 | 71 428 | 71 428 | |||||
| 2015-10-26 | 2015-10-22 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 4,40 | 28 572 | 28 572 | |||||
| 2015-10-26 | 2015-10-22 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 4,40 | 71 428 | 71 428 | |||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII-A, L.P. | CBIO | Common Stock | I | 1 256 411 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII-B, L.P. | CBIO | Common Stock | I | 1 212 855 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII, L.P. | CBIO | Common Stock | I | 2 248 142 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII, L.P. | CBIO | Common Stock | I | 2 248 142 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII-A, L.P. | CBIO | Common Stock | I | 1 256 411 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII-B, L.P. | CBIO | Common Stock | I | 1 212 855 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII, L.P. | CBIO | Common Stock | I | 2 248 142 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII-A, L.P. | CBIO | Common Stock | I | 1 256 411 | ||||||||
| 2015-08-31 | 3 | Essex Woodlands Health Ventures VIII, L.P. By Essex Woodlands Health Ventures Fund VIII-B, L.P. | CBIO | Common Stock | I | 1 212 855 | ||||||||
| 2015-08-31 | 2015-08-28 | 4 | HILL STEPHEN A | CBIO | Common Stock | D | 6,7200 | -12 146 | -82 | 15 711 | ||||
| 2015-08-20 | 2015-08-20 | 4 | USMAN NASSIM By The Usman Family Trust | CBIO | Warrant (Right to Buy) | I | 33,27 | 29 | 29 | |||||
| 2015-08-20 | 2015-08-20 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 11,52 | 22 508 | 22 508 | |||||
| 2015-08-20 | 2015-08-20 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 7,33 | 61 118 | 61 118 | |||||
| 2015-08-20 | 2015-08-20 | 4 | USMAN NASSIM | CBIO | Stock Option (Right to Buy) | D | 9,43 | 8 786 | 8 786 | |||||
| 2015-08-20 | 2015-08-20 | 4 | USMAN NASSIM By Nassim Usman IRA | CBIO | Common Stock | I | 13 528 | 74 375 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | USMAN NASSIM By The Usman Family Trust | CBIO | Common Stock | I | 60 847 | 60 847 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | SELICK HAROLD E | CBIO | Warrant (Right to Buy) | D | 33,27 | 287 | 287 | |||||
| 2015-08-20 | 2015-08-20 | 4 | SELICK HAROLD E | CBIO | Stock Option (Right to Buy) | D | 10,48 | 2 966 | 2 966 | |||||
| 2015-08-20 | 2015-08-20 | 4 | SELICK HAROLD E By Spouse | CBIO | Common Stock | I | 382 | 16 614 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | SELICK HAROLD E | CBIO | Common Stock | D | 16 232 | 16 232 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 6,03 | 14 325 | 14 325 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 7,60 | 2 440 | 2 440 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Payne Fletcher | CBIO | Stock Option (Right to Buy) | D | 7,60 | 7 320 | 7 320 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Payne Fletcher By Charles and Nancy Payne 2000 Trust | CBIO | Common Stock | I | 15 032 | 15 032 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | Madison Edwin | CBIO | Warrant (Right to Buy) | D | 33,27 | 29 | 29 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Madison Edwin | CBIO | Stock Option (Right to Buy) | D | 11,52 | 11 254 | 11 254 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Madison Edwin | CBIO | Stock Option (Right to Buy) | D | 10,48 | 6 501 | 6 501 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Madison Edwin | CBIO | Stock Option (Right to Buy) | D | 7,33 | 26 809 | 26 809 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Madison Edwin | CBIO | Stock Option (Right to Buy) | D | 9,43 | 3 820 | 3 820 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Madison Edwin | CBIO | Common Stock | D | 31 008 | 31 008 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | LAWLOR AUGUSTINE By HealthCare Ventures VIII, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 14 056 | 14 056 | |||||
| 2015-08-20 | 2015-08-20 | 4 | LAWLOR AUGUSTINE By HealthCare Ventures VIII, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 11 383 | 11 383 | |||||
| 2015-08-20 | 2015-08-20 | 4 | LAWLOR AUGUSTINE By HealthCare Ventures VIII, L.P. | CBIO | Warrant (Right to Buy) | I | 33,27 | 2 254 | 2 254 | |||||
| 2015-08-20 | 2015-08-20 | 4 | LAWLOR AUGUSTINE By HealthCare Ventures VIII, L.P. | CBIO | Common Stock | I | 1 041 024 | 1 041 024 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-B, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 687 | 687 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-A, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 1 580 | 1 580 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 21 926 | 21 926 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-B, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 556 | 556 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-A, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 1 280 | 1 280 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII, L.P. | CBIO | Warrant (Right to Buy) | I | 3,33 | 17 757 | 17 757 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-B, L.P. | CBIO | Warrant (Right to Buy) | I | 33,27 | 96 | 96 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-A, L.P. | CBIO | Warrant (Right to Buy) | I | 33,27 | 220 | 220 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII, L.P. | CBIO | Warrant (Right to Buy) | I | 33,27 | 3 065 | 3 065 | |||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-B, L.P. | CBIO | Common Stock | I | 33 503 | 1 179 352 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII-A, L.P. | CBIO | Common Stock | I | 77 059 | 1 145 849 | ||||||
| 2015-08-20 | 2015-08-20 | 4 | Himawan Jeff By Essex Woodlands Health Ventures Fund VIII, L.P. | CBIO | Common Stock | I | 1 068 790 | 1 068 790 | ||||||
| 2015-08-18 | 2015-08-14 | 4 | Rock Patrick C. | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-18 | 2015-08-14 | 4 | Hodges Mauri K | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-18 | 2015-08-14 | 4 | DUNTON ALAN W | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-18 | 2015-08-14 | 4 | Richard John P | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-18 | 2015-08-14 | 4 | HILL STEPHEN A | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-18 | 2015-08-14 | 4 | DESOUZA ERROL B | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-18 | 2015-08-14 | 4 | BROWN JULIA R | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-18 | 2015-08-14 | 4 | BLIXT CHARLES A | TRGT | Redeemable Convertible Note | D | 1,31 | |||||||
| 2015-08-05 | 2015-08-04 | 4 | DUNTON ALAN W | TRGT | Stock Option (Right to Buy) | D | 2,35 | 12 500 | 12 500 | |||||
| 2015-08-05 | 2015-08-04 | 4 | BLIXT CHARLES A | TRGT | Stock Option (Right to Buy) | D | 2,35 | 12 500 | 12 500 | |||||
| 2015-08-05 | 2015-08-04 | 4 | BROWN JULIA R | TRGT | Stock Option (Right to Buy) | D | 2,35 | 12 500 | 12 500 | |||||
| 2014-12-18 | 3/A | Hodges Mauri K | TRGT | Common Stock | D | 41 259 | ||||||||
| 2014-12-16 | 3 | Hodges Mauri K | TRGT | Common Stock | D | 2 318 | ||||||||
| 2014-12-16 | 3 | Hodges Mauri K | TRGT | Common Stock | D | 2 318 | ||||||||
| 2014-12-12 | 2014-12-11 | 4 | Richard John P | TRGT | Common Stock | D | 10 000 | 15 333 | ||||||
| 2014-12-12 | 2014-12-11 | 4 | DESOUZA ERROL B | TRGT | Common Stock | D | 10 000 | 15 333 | ||||||
| 2014-12-12 | 2014-12-11 | 4 | BROWN JULIA R | TRGT | Common Stock | D | 10 000 | 10 000 | ||||||
| 2014-12-12 | 2014-12-11 | 4 | BLIXT CHARLES A | TRGT | Common Stock | D | 10 000 | 10 000 | ||||||
| 2014-12-12 | 2014-12-11 | 4 | DUNTON ALAN W | TRGT | Common Stock | D | 10 000 | 10 000 | ||||||
| 2014-10-21 | 2014-10-17 | 4 | Musso Alan A | TRGT | Common Stock | D | 55 000 | 57 799 | ||||||
| 2014-10-21 | 2014-10-17 | 4 | HILL STEPHEN A | TRGT | Common Stock | D | 175 000 | 195 000 | ||||||
| 2014-10-21 | 2014-10-17 | 4 | Rock Patrick C. | TRGT | Common Stock | D | 45 000 | 45 000 | ||||||
| 2014-10-21 | 2014-10-17 | 4 | Toler Steven M. | TRGT | Common Stock | D | 45 000 | 46 000 | ||||||
| 2014-06-13 | 2014-06-12 | 4 | BLIXT CHARLES A | TRGT | Stock Option (Right to Buy) | D | 4,29 | 12 500 | 12 500 | |||||
| 2014-06-13 | 2014-06-12 | 4 | BROWN JULIA R | TRGT | Stock Option (Right to Buy) | D | 4,29 | 12 500 | 12 500 | |||||
| 2014-06-13 | 2014-06-12 | 4 | DESOUZA ERROL B | TRGT | Stock Option (Right to Buy) | D | 4,29 | 12 500 | 12 500 | |||||
| 2014-06-13 | 2014-06-12 | 4 | Richard John P | TRGT | Stock Option (Right to Buy) | D | 4,29 | 17 500 | 17 500 | |||||
| 2014-06-13 | 2014-06-12 | 4 | DUNTON ALAN W | TRGT | Stock Option (Right to Buy) | D | 4,29 | 12 500 | 12 500 | |||||
| 2014-01-24 | 2014-01-23 | 4 | HILL STEPHEN A | TRGT | Stock Option (Right to Buy) | D | 4,74 | 175 000 | 175 000 | |||||
| 2014-01-24 | 2014-01-23 | 4 | Musso Alan A | TRGT | Stock Option (Right to Buy) | D | 4,74 | 55 000 | 55 000 | |||||
| 2014-01-24 | 2014-01-23 | 4 | Toler Steven M. | TRGT | Stock Option (Right to Buy) | D | 4,74 | 45 000 | 45 000 | |||||
| 2014-01-24 | 2014-01-23 | 4 | Hosford David A. | TRGT | Stock Option (Right to Buy) | D | 4,74 | 45 000 | 45 000 | |||||
| 2014-01-24 | 2014-01-23 | 4 | Rock Patrick C. | TRGT | Stock Option (Right to Buy) | D | 4,74 | 45 000 | 45 000 | |||||
| 2014-01-17 | 2014-01-08 | 4/A | Richard John P | TRGT | Common Stock, $0.001 par value per share | D | 4,31 | -10 000 | 10 000 | |||||
| 2014-01-09 | 2014-01-08 | 4 | Richard John P | TRGT | Common Stock, $0.001 par value per share | D | 4,31 | 10 000 | 10 000 | |||||
| 2013-12-05 | 2013-12-05 | 4 | BARRIS PETER J See Note 2 | TRGT | Common Stock | I | 5,1310 | -1 000 | -5 | 0 | ||||
| 2013-12-05 | 2013-12-05 | 4 | BARRETT M JAMES See Note 3 | TRGT | Common Stock | I | 5,1310 | -1 000 | -5 | 0 | ||||
| 2013-12-05 | 2013-12-03 | 4 | BARRETT M JAMES | TRGT | Director Stock Option (right to buy) | D | 4,16 | -7 500 | 0 | |||||
| 2013-12-05 | 2013-12-03 | 4 | BARRETT M JAMES | TRGT | Director Stock Option (right to buy) | D | 2,71 | -7 500 | 0 | |||||
| 2013-12-05 | 2013-12-03 | 4 | BARRETT M JAMES | TRGT | Common Stock | D | 5,3836 | -15 000 | -81 | 0 | ||||
| 2013-12-05 | 2013-12-03 | 4 | BARRETT M JAMES | TRGT | Common Stock | D | 4,1600 | 7 500 | 31 | 15 000 | ||||
| 2013-12-05 | 2013-12-03 | 4 | BARRETT M JAMES | TRGT | Common Stock | D | 2,7100 | 7 500 | 20 | 7 500 | ||||
| 2013-12-05 | 2013-12-05 | 4 | SANDELL SCOTT D See Note 2 | TRGT | Common Stock | I | 5,1310 | -1 000 | -5 | 0 | ||||
| 2013-11-22 | 2013-11-21 | 4 | BARRIS PETER J See Note 2 | TRGT | Common Stock | I | 5,1627 | -5 333 | -28 | 1 000 | ||||
| 2013-11-22 | 2013-11-21 | 4 | BARRETT M JAMES See Note 2 | TRGT | Common Stock | I | 5,1627 | -5 333 | -28 | 1 000 | ||||
| 2013-11-22 | 2013-11-21 | 4 | SANDELL SCOTT D See Note 2 | TRGT | Common Stock | I | 5,1627 | -5 333 | -28 | 1 000 | ||||
| 2013-10-01 | 2013-09-30 | 4 | Rock Patrick C. | TRGT | Common Stock, $0.001 par value per share | D | 5,31 | 100 000 | 100 000 | |||||
| 2013-06-10 | 2013-06-07 | 4 | BLIXT CHARLES A | TRGT | Stock Option (Right to Buy) | D | 5,23 | 12 500 | 12 500 | |||||
| 2013-06-10 | 2013-06-07 | 4 | BROWN JULIA R | TRGT | Stock Option (Right to Buy) | D | 5,23 | 12 500 | 12 500 | |||||
| 2013-06-10 | 2013-06-07 | 4 | SKALETSKY MARK B | TRGT | Stock Option (Right to Buy) | D | 5,23 | 17 500 | 17 500 | |||||
| 2013-06-10 | 2013-06-07 | 4 | DESOUZA ERROL B | TRGT | Stock Option (Right to Buy) | D | 5,23 | 12 500 | 12 500 | |||||
| 2013-06-10 | 2013-06-07 | 4 | Richard John P | TRGT | Stock Option (Right to Buy) | D | 5,23 | 12 500 | 12 500 | |||||
| 2013-06-10 | 2013-06-07 | 4 | DUNTON ALAN W | TRGT | Stock Option (Right to Buy) | D | 5,23 | 12 500 | 12 500 | |||||
| 2013-06-04 | 2013-06-03 | 4 | BARRIS PETER J See Note 1 | TRGT | Stock Option (Right to Buy) | I | 0,08 | -1 000 | 0 | |||||
| 2013-06-04 | 2013-06-03 | 4 | BARRIS PETER J See Note 1 | TRGT | Common Stock | I | 0,0750 | 1 000 | 0 | 6 333 | ||||
| 2013-06-04 | 2013-06-03 | 4 | BARRETT M JAMES See Note 1 | TRGT | Stock Option (Right to Buy) | I | 0,08 | -1 000 | 0 | |||||
| 2013-06-04 | 2013-06-03 | 4 | BARRETT M JAMES See Note 1 | TRGT | Common Stock | I | 0,0750 | 1 000 | 0 | 6 333 | ||||
| 2013-06-04 | 2013-06-03 | 4 | SANDELL SCOTT D See Note 1 | TRGT | Stock Option (Right to Buy) | I | 0,08 | -1 000 | 0 | |||||
| 2013-06-04 | 2013-06-03 | 4 | SANDELL SCOTT D See Note 1 | TRGT | Common Stock | I | 0,0750 | 1 000 | 0 | 6 333 | ||||
| 2013-05-13 | 2013-05-10 | 4 | BROWN JULIA R By Julia R. Brown Trust | TRGT | Common Stock | I | 5,0890 | 6 000 | 31 | 6 000 | ||||
| 2013-03-11 | 2013-03-11 | 4/A | HILL STEPHEN A | TRGT | Common Stock | D | 4,3781 | 10 000 | 44 | 20 000 | ||||
| 2013-03-11 | 2013-03-08 | 4/A | HILL STEPHEN A | TRGT | Common Stock | D | 4,4796 | 10 000 | 45 | 10 000 | ||||
| 2013-03-11 | 2013-03-11 | 4 | HILL STEPHEN A | TRGT | Common Stock | D | 4,3781 | 10 000 | 44 | 20 000 | ||||
| 2013-03-11 | 2013-03-08 | 4 | HILL STEPHEN A | TRGT | Common Stock | D | 4,4796 | 10 000 | 45 | 10 000 | ||||
| 2013-01-18 | 2013-01-17 | 4 | Musso Alan A | TRGT | Stock Option (Right to Buy) | D | 4,63 | 65 000 | 65 000 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Bencherif Merouane | TRGT | Stock Option (Right to Buy) | D | 4,63 | 40 000 | 40 000 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Brennan Jeffrey P | TRGT | Stock Option (Right to Buy) | D | 4,63 | 65 000 | 65 000 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Zorn Peter A | TRGT | Stock Option (Right to Buy) | D | 4,63 | 65 000 | 65 000 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Hodges Mauri K | TRGT | Stock Option (Right to Buy) | D | 4,63 | 40 000 | 40 000 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Hicks Karen A | TRGT | Stock Option (Right to Buy) | D | 4,63 | 40 000 | 40 000 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Toler Steven M. | TRGT | Stock Option (Right to Buy) | D | 4,63 | 45 000 | 45 000 | |||||
| 2013-01-18 | 2013-01-17 | 4 | Hosford David A. | TRGT | Stock Option (RIght to Buy) | D | 4,63 | 45 000 | 45 000 | |||||
| 2013-01-11 | 3 | INVESTMENT 10 LLC By Biotechnology Value Fund, L.P. | TRGT | Common Stock, $0.001 par value | I | 2 977 919 | ||||||||
| 2013-01-11 | 3 | INVESTMENT 10 LLC By Biotechnology Value Fund II, L.P. | TRGT | Common Stock, $0.001 par value | I | 1 713 907 | ||||||||
| 2013-01-11 | 3 | INVESTMENT 10 LLC By BVF Investments, L.L.C. | TRGT | Common Stock, $0.001 par value | I | 349 482 | ||||||||
| 2013-01-11 | 3 | INVESTMENT 10 LLC | TRGT | Common Stock, $0.001 par value | D | 1 130 361 | ||||||||
| 2012-12-05 | 3 | HILL STEPHEN A | TRGT | No securities are beneficially owned | D | 0 | ||||||||
| 2012-12-05 | 2012-12-03 | 4 | HILL STEPHEN A | TRGT | Stock Option (Right to Buy) | D | 4,50 | 400 000 | 400 000 | |||||
| 2012-11-20 | 2012-11-16 | 4/A | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 3,9997 | 217 000 | 868 | 1 713 907 | ||||
| 2012-11-20 | 2012-11-16 | 4/A | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 3,9997 | 378 000 | 1 512 | 2 977 919 | ||||
| 2012-11-20 | 2012-11-19 | 4 | KRAMLICH C RICHARD See Note 1 | TRGT | Stock Option (Right to Buy) | I | 0,08 | -3 333 | 0 | |||||
| 2012-11-20 | 2012-11-19 | 4 | KRAMLICH C RICHARD See Note 1 | TRGT | Common Stock | I | 0,0750 | 3 333 | 0 | 5 333 | ||||
| 2012-11-20 | 2012-11-19 | 4 | BARRIS PETER J See Note 1 | TRGT | Stock Option (Right to Buy) | I | 0,08 | -3 333 | 0 | |||||
| 2012-11-20 | 2012-11-19 | 4 | BARRIS PETER J See Note 1 | TRGT | Common Stock | I | 0,0750 | 3 333 | 0 | 5 333 | ||||
| 2012-11-20 | 2012-11-19 | 4 | SANDELL SCOTT D See Note 1 | TRGT | Stock Option (Right to Buy) | I | 0,08 | -3 333 | 0 | |||||
| 2012-11-20 | 2012-11-19 | 4 | SANDELL SCOTT D See Note 1 | TRGT | Common Stock | I | 0,0750 | 3 333 | 0 | 5 333 | ||||
| 2012-11-19 | 2012-11-16 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 5,1083 | 26 800 | 137 | 1 523 707 | ||||
| 2012-11-19 | 2012-11-16 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 5,1083 | 46 700 | 239 | 2 646 619 | ||||
| 2012-11-19 | 2012-11-14 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0000 | 444 649 | 1 779 | 1 496 907 | ||||
| 2012-11-19 | 2012-11-14 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0000 | 772 063 | 3 088 | 2 599 919 | ||||
| 2012-11-09 | 2012-11-08 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0068 | 17 400 | 70 | 1 052 258 | ||||
| 2012-11-09 | 2012-11-08 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0068 | 31 929 | 128 | 1 827 856 | ||||
| 2012-11-09 | 2012-11-07 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0812 | 8 800 | 36 | 1 034 858 | ||||
| 2012-11-09 | 2012-11-07 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0812 | 14 300 | 58 | 1 795 927 | ||||
| 2012-11-02 | 2012-11-02 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0535 | 21 500 | 87 | 1 026 058 | ||||
| 2012-11-02 | 2012-11-02 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0535 | 36 100 | 146 | 1 781 627 | ||||
| 2012-11-02 | 2012-11-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | CommonStock | I | 4,0465 | 23 400 | 95 | 1 004 558 | ||||
| 2012-11-02 | 2012-11-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0465 | 6 700 | 27 | 1 745 527 | ||||
| 2012-11-02 | 2012-10-31 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0557 | 5 300 | 21 | 981 158 | ||||
| 2012-11-02 | 2012-10-31 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | TRGT | Common Stock | I | 4,0557 | 46 700 | 189 | 1 738 827 | ||||
| 2012-09-10 | 3 | LAMPERT MARK N By BVF Investments, L.L.C. | TRGT | Common Stock, $0.001 par value | I | 349 482 | ||||||||
| 2012-09-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | TRGT | Common Stock, $0.001 par value | I | 1 692 127 | ||||||||
| 2012-09-10 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | TRGT | Common Stock, $0.001 par value | I | 975 858 | ||||||||
| 2012-08-01 | 2012-07-31 | 4 | BURRILL STEVEN By Burrill & Company LLC | TRGT | Stock Option (Right to Buy) | I | 0,08 | -4 333 | 0 | |||||
| 2012-08-01 | 2012-07-31 | 4 | BURRILL STEVEN By Burrill & Company LLC | TRGT | Common Stock | I | 0,0750 | 4 333 | 0 | 4 333 | ||||
| 2012-08-01 | 3 | Hosford David A. | TRGT | Common Stock | D | 600 | ||||||||
| 2012-06-13 | 2012-06-11 | 4 | SKALETSKY MARK B | TRGT | Stock Option (Right to Buy) | D | 4,20 | 57 500 | 57 500 | |||||
| 2012-06-11 | 2012-06-07 | 4 | BARRETT M JAMES | TRGT | Director Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-06-11 | 2012-06-08 | 4 | Richard John P By trust | TRGT | Common Stock | I | 4,1590 | 7 500 | 31 | 7 500 | ||||
| 2012-06-11 | 3 | Toler Steven M. | TRGT | Common Stock | D | 1 000 | ||||||||
| 2012-06-08 | 2012-06-07 | 4 | BLIXT CHARLES A | TRGT | Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-06-08 | 2012-06-07 | 4 | BROWN JULIA R | TRGT | Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-06-08 | 2012-06-07 | 4 | SNYDERMAN RALPH | TRGT | Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-06-08 | 2012-06-07 | 4 | BURRILL STEVEN | TRGT | Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-06-08 | 2012-06-07 | 4 | DESOUZA ERROL B | TRGT | Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-06-08 | 2012-06-07 | 4 | Richard John P | TRGT | Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-06-08 | 2012-06-07 | 4 | DUNTON ALAN W | TRGT | Stock Option (Right to Buy) | D | 4,16 | 7 500 | 7 500 | |||||
| 2012-05-22 | 2012-05-18 | 4 | Bencherif Merouane | TRGT | Stock Option (Right to Buy) | D | 2,93 | -15 938 | 7 970 | |||||
| 2012-05-22 | 2012-05-18 | 4 | Bencherif Merouane | TRGT | Common Stock | D | 2,9300 | 15 938 | 47 | 15 938 | ||||
| 2012-05-08 | 2012-05-04 | 4 | Musso Alan A | TRGT | Stock Option (Right to Buy) | D | 4,59 | 100 000 | 100 000 | |||||
| 2012-05-08 | 2012-05-04 | 4 | Bencherif Merouane | TRGT | Stock Option (Right to Buy) | D | 4,59 | 90 000 | 90 000 | |||||
| 2012-05-08 | 2012-05-04 | 4 | deBethizy J Donald | TRGT | Stock Option (Right to Buy) | D | 4,59 | 135 000 | 135 000 | |||||
| 2012-05-08 | 2012-05-04 | 4 | Brennan Jeffrey P | TRGT | Stock Option (Right to Buy) | D | 4,59 | 100 000 | 100 000 | |||||
| 2012-05-08 | 2012-05-04 | 4 | Zorn Peter A | TRGT | Stock Option (Right to Buy) | D | 4,59 | 100 000 | 100 000 | |||||
| 2012-05-08 | 2012-05-04 | 4 | Hicks Karen A | TRGT | Stock Option (Right to Buy) | D | 4,59 | 60 000 | 60 000 | |||||
| 2012-05-08 | 2012-05-04 | 4 | Hodges Mauri K | TRGT | Stock Option (Right to Buy) | D | 4,59 | 60 000 | 60 000 | |||||
| 2012-02-16 | 2012-02-14 | 4 | deBethizy J Donald | TRGT | Stock Option (Right to Buy) | D | 5,10 | -798 | 0 | |||||
| 2012-02-16 | 2012-02-14 | 4 | deBethizy J Donald | TRGT | Common Stock | D | 5,1000 | 798 | 4 | 798 | ||||
| 2010-04-22 | 3 | Hicks Karen A | TRGT | Common Stock | D | 4 226 | ||||||||
| 2010-04-22 | 3 | Hodges Mauri K | TRGT | Common Stock | D | 1 159 | ||||||||
| 2007-03-07 | 2006-10-25 | 4/A | DUNTON ALAN W | TRGT | Stock option (right to buy) | D | 5,69 | 25 000 | 25 000 | |||||
| 2007-02-27 | 2007-02-23 | 4 | Jones Elaine V By EuclidSR Biotechnology Partners L.P. | TRGT | Stock Option (Right to Buy) | I | 0,08 | -197 | 0 | |||||
| 2007-02-27 | 2007-02-23 | 4 | Jones Elaine V By EuclidSR Partners L.P. | TRGT | Stock Option (Right to Buy) | I | 0,08 | -803 | 0 | |||||
| 2007-02-27 | 2007-02-23 | 4 | Jones Elaine V By EuclidSR Biotechnology Partners, L.P. | TRGT | Common Stock | I | 0,0750 | 197 | 0 | 371 945 | ||||
| 2007-02-27 | 2007-02-23 | 4 | Jones Elaine V By EuclidSR Partners, L.P. | TRGT | Common Stock | I | 0,0750 | 803 | 0 | 1 510 883 | ||||
| 2006-08-18 | 3 | BURRILL STEVEN By Burrill Biotechnology Capital Fund L.P. | TRGT | Common Stock | I | 778 062 | ||||||||
| 2006-08-18 | 3 | BURRILL STEVEN By Burrill & Company LLC | TRGT | Common Stock | I | 1 000 | ||||||||
| 2006-05-08 | 2006-04-18 | 4/A | NOMURA INTERNATIONAL PLC Owned by NLP | TRGT | Common Stock | I | 946 428 | 946 428 | ||||||
| 2006-05-08 | 2006-04-18 | 4/A | NOMURA INTERNATIONAL PLC | TRGT | Common Stock | D | 1 190 476 | 2 136 904 | ||||||
| 2006-04-20 | 2006-04-18 | 4 | NOMURA INTERNATIONAL PLC Owned by NLP | TRGT | Series C Convertible Preferred Stock | I | -6 570 248 | 0 | ||||||
| 2006-04-20 | 2006-04-18 | 4 | NOMURA INTERNATIONAL PLC | TRGT | Series C Convertible Preferred Stock | D | -8 264 462 | 0 | ||||||
| 2006-04-20 | 2006-04-18 | 4 | NOMURA INTERNATIONAL PLC Owned by NLP | TRGT | Common Stock | I | 946 428 | 946 428 | ||||||
| 2006-04-20 | 2006-04-18 | 4 | NOMURA INTERNATIONAL PLC | TRGT | Common Stock | D | 1 190 476 | 2 136 904 | ||||||
| 2006-04-11 | 3 | BLIXT CHARLES A By R.J. Reynolds Tobacco Holdings, Inc. | TRGT | Common Stock | I | 4 333 | ||||||||
| 2006-04-11 | 3 | DESOUZA ERROL B | TRGT | Common Stock | D | 1 000 | ||||||||
| 2006-04-11 | 3 | Richard John P | TRGT | Common Stock | D | 4 333 | ||||||||
| 2006-04-11 | 3 | Bencherif Merouane | TRGT | Common Stock | D | 7 735 | ||||||||
| 2006-04-11 | 3 | Caldwell William S | TRGT | Common Stock | D | 7 735 | ||||||||
| 2006-04-11 | 3 | deBethizy J Donald | TRGT | Common Stock | D | 93 835 | ||||||||
| 2006-04-11 | 3 | Dunbar Geoffrey C | TRGT | Common Stock | D | 22 602 | ||||||||
| 2006-04-11 | 3 | HANHAM ANN By Burrill & Company LLC | TRGT | Common Stock | I | 1 000 | ||||||||
| 2006-04-11 | 3 | Musso Alan A | TRGT | Common Stock | D | 2 799 | ||||||||
| 2006-04-11 | 3 | SKALETSKY MARK B | TRGT | Common Stock | D | 11 332 |
P
Otwarty rynek lub prywatny zakup niepochodnych lub pochodnych papierów wartościowych
S
Otwarty rynek lub prywatna sprzedaż niepochodnych lub pochodnych papierów wartościowych
A
Grant, nagroda lub inne nabycie papierów wartościowych od spółki (np. opcja)
C
Konwersja instrumentu pochodnego
D
Sprzedaż lub przeniesienie papierów wartościowych z powrotem do spółki
F
Zapłata ceny wykonania lub zobowiązania podatkowego z wykorzystaniem części papierów wartościowych otrzymanych od spółki
G
Darowizna papierów wartościowych przez lub na rzecz insidera
K
Swapy kapitałowe i podobne transakcje zabezpieczające
M
Wykonanie lub konwersja pochodnego papieru wartościowego otrzymanego od spółki (takiego jak opcja)
V
Transakcja dobrowolnie zgłoszona na Formularzu 4
J
Inne (wraz z przypisem opisującym transakcję)
